Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572797 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9890711 | 0.86 | HPGD (0.42) | SMN1; SMN2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9890749 | 0.82 | P2RX7 (0.46) | MEN1KMT2APTGS2 | |
| SCHEMBL2395314 | 0.81 | RAB9A (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9890752 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL9890755 | 0.80 | GRIN1 (0.42) | SMN1; SMN2KMT2AALDH1A1RAB9ALMNA | |
| SCHEMBL5298485 | 0.79 | NPC1 (0.54) | SMN1; SMN2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL8568769 | 0.76 | P2RX7 (0.49) | SMN1; SMN2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2391383 | 0.76 | SLC6A4 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL2393439 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374790-A1 | BIPHENYLACETAMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |