Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.40 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9890755 | 0.89 | GRIN1 (0.42) | SMN1; SMN2CSNK1DKCNA5KCNK3KCNK5 | |
| SCHEMBL9890711 | 0.84 | HPGD (0.42) | SMN1; SMN2ALDH1A1GAAKMT2ARAB9A | |
| SCHEMBL9890744 | 0.83 | SLC9A1 (0.41) | SMN1; SMN2CSNK1DLMNAABL1MAPT | |
| SCHEMBL9892661 | 0.83 | P2RX7 (0.42) | SMN1; SMN2CSNK1DKCNA5KCNK3KCNK5 | |
| SCHEMBL9890732 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL9892682 | 0.80 | P2RX7 (0.42) | SMN1; SMN2KCNA5KCNK3KCNK5KCNK17 | |
| SCHEMBL9890731 | 0.80 | LMNA (0.48) | SMN1; SMN2KCNA5ALDH1A1LMNAMAPT | |
| SCHEMBL12201835 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL2391383 | 0.80 | SLC6A4 (0.49) | SMN1; SMN2KCNA5ALDH1A1LMNAKMT2A | |
| SCHEMBL2395314 | 0.79 | RAB9A (0.49) | SMN1; SMN2ALDH1A1LMNAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142771-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | SMN1; SMN2 2980/4885CSNK1D 3595/4885KCNA5 41/4885 |
| US-20110224304-A1 | BIPHENYLACETAMIDE DERIVATIVE | HRH3, KCNH3, BRPF3 | SMN1; SMN2 2980/4885CSNK1D 3595/4885KCNA5 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.