Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558175 | 0.88 | HSP90AA1 (0.36) | KDM4ENAPRTHCAR2HSP90AA1ADORA3 | |
| SCHEMBL9287991 | 0.73 | SLC6A3 (0.42) | KDM4ETSHRADRA1A | |
| SCHEMBL10715470 | 0.72 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL4564370 | 0.72 | KDM4E (0.34) | KDM4ENAPRTHCAR2HSP90AA1ADORA3 | |
| SCHEMBL1919145 | 0.72 | KDM4E (0.33) | KDM4ENAPRTHCAR2HSP90AA1ADORA3 | |
| SCHEMBL11788487 | 0.72 | HSP90AA1 (0.33) | HSP90AA1 | |
| SCHEMBL13397712 | 0.72 | KDM4E (0.34) | KDM4EHSP90AA1 | |
| SCHEMBL8427620 | 0.72 | LMNA (0.37) | KDM4ENAPRTHCAR2HSP90AA1ADORA3 | |
| Bromide SCHEMBL15567663 | 0.71 | KDM4E (0.32) | KDM4ENAPRTHCAR2HSP90AA1ADORA3 | |
| SCHEMBL10715529 | 0.70 | KDM4E (0.41) | KDM4ENAPRTHCAR2ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383793-B1 | INSULIN AND IGF-1 RECEPTOR AGONISTS AND ANTAGONISTS | DGI BIOTECHNOLOGIES L L C (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2368902-A2 | Insulin and IGF-1 receptor agonists and antagonists | DGI Bio Technologies LLC (US) | 2011-09-28 | — | — | EP | disclosed |