Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21842124 | 0.76 | SMN1; SMN2 (0.54) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL21842123 | 0.76 | SMN1; SMN2 (0.54) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL21842364 | 0.76 | SMN1; SMN2 (0.54) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12204305 | 0.74 | OPRL1 (0.42) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12204203 | 0.74 | FOXM1 (0.49) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12204207 | 0.72 | FOXM1 (0.68) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12204109 | 0.72 | OPRL1 (0.50) | FOXM1SMN1; SMN2KDM4EALDH1A1OPRL1 | |
| SCHEMBL16281580 | 0.71 | KDM4E (0.51) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12204097 | 0.70 | OPRL1 (0.49) | FOXM1SMN1; SMN2KDM4EALDH1A1OPRL1 | |
| SCHEMBL24437848 | 0.69 | CYP1A2 (0.57) | FOXM1SMN1; SMN2KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |