Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.42 |
| ▸ | FOXM1 | Q08050 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204763 | 0.81 | FOXM1 (0.46) | FOXM1EPHX2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12204203 | 0.77 | FOXM1 (0.49) | OPRL1FOXM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12204106 | 0.76 | IDO1 (0.48) | OPRL1FOXM1KDM4E | |
| SCHEMBL12204080 | 0.74 | FOXM1 (0.42) | OPRL1FOXM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18677297 | 0.73 | EPHX2 (0.48) | OPRL1EPHX2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12204207 | 0.70 | FOXM1 (0.68) | FOXM1KDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL19055379 | 0.70 | SLC6A2 (0.39) | KDM4EALDH1A1SMN1; SMN2GNRHR | |
| SCHEMBL12204109 | 0.69 | OPRL1 (0.50) | OPRL1FOXM1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21722976 | 0.68 | SLC6A4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL7018005 | 0.67 | FOXM1 (0.68) | FOXM1KDM4EALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377856-A1 | Urea glucokinase activators | NOVO NORDISK A/S (DK) | 2011-10-19 | — | — | EP | disclosed |