SCHEMBL12205709

SCHEMBL12205709

CC(O)NC(=O)c1cccc(C(=O)NC(C)O)c1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
GAA P10253 1/20 0.56
HSD17B10 Q99714 1/20 0.56
NPSR1 Q6W5P4 1/20 0.53
ALDH1A1 P00352 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
ATM Q13315 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
THRB P10828 1/20 0.47
MEN1 O00255 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
ERN1 O75460 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536043 0.87 ALDH1A1 (0.53) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL8593124 0.85 NPSR1 (0.69) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL6834922 0.85 ALDH1A1 (0.56) KMT2AHSD17B10ALDH1A1HDAC8HDAC6
SCHEMBL27817512 0.82 HPGD (0.52) KMT2AALDH1A1HDAC8HDAC6SMN1; SMN2
SCHEMBL6835145 0.82 KMT2A (0.61) KMT2AALDH1A1ATMSMN1; SMN2LMNA
SCHEMBL12608268 0.80 NPSR1 (0.50) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL14355565 0.79 NPSR1 (0.61) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL13753397 0.79 NPSR1 (0.61) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL12608266 0.79 GAA (0.51) KMT2AGAAHSD17B10NPSR1ALDH1A1
SCHEMBL11081421 0.79 NPSR1 (0.53) KMT2AGAAHSD17B10NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8309629-B2 Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate FUJIFILM CORPORATION (JP) 2012-11-13 US disclosed
EP-1096314-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2011-10-19 EP disclosed
EP-1988136-B1 Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate FUJIFILM CORP (JP) 2010-09-01 EP disclosed
US-20100075251-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100055615-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20100047537-A1 METHOD OF PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-7531288-B2 Negative-working excellent in preservation stability and exhibits high sensitivity and good printing durability; hydrophilic support; and a photosensitive layer containing a polymerization initiator, a chain transfer agent, a compound having an ethylenically unsaturated double bond and a polymer binder FUJIFILM CORPORATION (JP) 2009-05-12 US disclosed
US-20090087790-A1 METHOD OF PRODUCING A NEGATIVE PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-7449282-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-11-11 US disclosed
EP-1988136-A1 Ink composition, inkjet recording method, printed material, method for producing planographic printing plate, and planographic printing plate FUJIFILM Corporation (JP) 2008-11-05 EP disclosed
US-20080213550-A1 INK COMPOSITION, INKJET RECORDING METHOD, PRINTED MATERIAL, METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE, AND PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed
US-7368544-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-05-06 US disclosed
US-7314698-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed