SCHEMBL6834922

SCHEMBL6834922

CC(O)NC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HPGD P15428 2/20 0.56
RAB9A P51151 1/20 0.56
HDAC1 Q13547 2/20 0.52
HDAC3 O15379 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
IDO1 P14902 1/20 0.52
ALOX15 P16050 1/20 0.52
CA9 Q16790 1/20 0.52
HDAC7 Q8WUI4 1/20 0.52
HDAC2 Q92769 1/20 0.52
HSD17B10 Q99714 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
LMNA P02545 4/20 0.52
SLC1A2 P43004 1/20 0.52
KMT2A Q03164 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27817512 0.89 HPGD (0.52) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL12205709 0.85 KMT2A (0.56) ALDH1A1SMN1; SMN2HPGDHSD17B10HDAC8
SCHEMBL29772431 0.84 MLYCD (0.58) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL155518 0.84 MLYCD (0.58) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL9783640 0.84 HDAC1 (0.60) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL24998749 0.84 MLYCD (0.58) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL13495008 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL14828665 0.83 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
Hydrochloric Acid SCHEMBL7849680 0.83 MLYCD (0.56) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1
SCHEMBL2446701 0.83 SMN1; SMN2 (0.61) ALDH1A1SMN1; SMN2HPGDRAB9AHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103000-A1 PREPARATION METHOD FOR N-ALKENYL AMIDE 中国石油化工股份有限公司 2025-05-22 WO claimed
CN-120020117-A Process for the preparation of N-vinylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
WO-2025103000-A1 PREPARATION METHOD FOR N-ALKENYL AMIDE 中国石油化工股份有限公司 2025-05-22 WO disclosed
CN-120020117-A Process for the preparation of N-vinylamides 中国石油化工股份有限公司 2025-05-20 CN disclosed
CN-106543058-B A kind of chirality selenium carbamide compounds and its preparation and application 中国科学院福建物质结构研究所 2019-09-20 CN disclosed
US-8049037-B2 Sphingosine-1-phosphate (S1P) receptor antagonists and methods for use thereof ALLERGAN, INC. (US) 2011-11-01 US disclosed
US-20100041715-A1 SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONISTS AND METHODS FOR USE THEREOF ALLERGAN, INC. (US) 2010-02-18 US disclosed
US-20040082774-A1 Novel phosphate and thiophosphate protecting groups ISIS PHARMACEUTICALS, INC. 2004-04-29 US disclosed
US-6610837-B1 Preparation of an oligonucleotide compound of given formula by reacting with given compounds, followed by oxidation or sulfurization ISIS PHARMACEUTICALS, INC. 2003-08-26 US disclosed
WO-2000055179-A1 NOVEL PHOSPHATE AND THIOPHOSPHATE PROTECTING GROUPS ISIS PHARMACEUTICALS, INC. (US) 2000-09-21 WO disclosed
US-6121437-A SYNTHESIS OF OLIGONUCLEOTIDES USING OLIGONUCLEOTIDES OR NUCLEOTIDES WITH PROTECTED INTERNUCLEOSIDIC PHOSPHORUS FUNCTIONALITIES WHICH CAN BE REMOVED UNDER MILD CONDITIONS AND PRODUCE NONTOXIC BY-PRODUCTS ISIS PHARMACEUTICALS, INC. (US) 2000-09-19 US disclosed
WO-1995024883-A1 COMPOSITIONS FOR RETARDING AND PREVENTING HAIR LOSS LADRON DE CEGAMA ANGEL (ES) 1995-09-21 WO disclosed
EP-0522606-A2 Pyridine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041715-A1 SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR ANTAGONISTS AND METHODS FOR USE THEREOF S1PR1, S1PR2, S1PR3 ALDH1A1 2830/4885SMN1; SMN2 1727/4885HPGD 2890/4885
US-20040082774-A1 Novel phosphate and thiophosphate protecting groups TYMP, MTAP, PPIP5K2 ALDH1A1 4612/4885SMN1; SMN2 1704/4885HPGD 3873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.