Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MLYCD | O95822 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12093587 | 0.91 | HPGD (0.65) | HPGDMLYCDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9425774 | 0.91 | GFER (0.52) | HPGDMLYCDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12089430 | 0.89 | RAB9A (0.50) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8587216 | 0.89 | NPC1 (0.57) | HPGDMLYCDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6834922 | 0.89 | ALDH1A1 (0.56) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6835136 | 0.86 | CA1 (0.61) | SMN1; SMN2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL18579396 | 0.86 | ALDH1A1 (0.62) | HPGDKMT2AALDH1A1HTTLMNA | |
| SCHEMBL17313750 | 0.84 | MEN1 (0.45) | HPGDMLYCDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8982349 | 0.84 | ALDH1A1 (0.49) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11163745 | 0.83 | RAB9A (0.61) | HPGDSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161626-A | Diamide compound with two acrylates and preparation method and application thereof | UNIV HEFEI TECHNOLOGY | 2011-08-24 | — | — | CN | disclosed |