Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718228 | 0.81 | KDM4E (0.56) | ITGB3ITGB1ITGAVITGA5ITGA4 | |
| SCHEMBL31234028 | 0.77 | SMN1; SMN2 (0.67) | ALDH1A1HPGDTSHRHSD17B10NAMPT | |
| SCHEMBL8740407 | 0.74 | ALDH1A1 (0.60) | HDAC3HDAC1HDAC2ALDH1A1HPGD | |
| SCHEMBL28943283 | 0.73 | TRPV1 (0.70) | TRPV1 | |
| SCHEMBL28943286 | 0.73 | TRPV1 (0.70) | TRPV1 | |
| Hydrochloric Acid SCHEMBL10715386 | 0.73 | ALDH1A1 (0.59) | HDAC3HDAC1HDAC2ALDH1A1HPGD | |
| SCHEMBL11987478 | 0.72 | KMT2A (0.66) | TRPV1ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL14291922 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSD17B10NAMPT | |
| SCHEMBL15503309 | 0.71 | ALDH1A1 (0.71) | HDAC3HDAC1HDAC2ALDH1A1HPGD | |
| SCHEMBL13753557 | 0.71 | MEN1 (0.51) | TRPV1ALDH1A1HPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380631-A1 | Heteroaryl derivatives as DGAT1 inhibitors | Novartis AG (CH) | 2011-10-26 | — | — | EP | disclosed |