Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105015 | 0.82 | ITGB3 (0.72) | KDM4ENPSR1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11720348 | 0.81 | ALDH1A1 (0.51) | KDM4ENPSR1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12206187 | 0.81 | TRPV1 (0.58) | NPSR1L3MBTL1ALDH1A1TSHRITGB3 | |
| SCHEMBL30009081 | 0.80 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL31234028 | 0.80 | SMN1; SMN2 (0.67) | KDM4EALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL13450010 | 0.77 | KDM4E (0.70) | KDM4EL3MBTL1TSHRRAB9ANPC1 | |
| SCHEMBL25668731 | 0.75 | TSHR (0.56) | KDM4EL3MBTL1ALDH1A1TSHRRAB9A | |
| SCHEMBL13366272 | 0.74 | RAB9A (0.64) | KDM4ENPSR1ALDH1A1TSHRRAB9A | |
| SCHEMBL17674635 | 0.74 | TRPM8 (0.63) | KDM4ENPSR1L3MBTL1RAB9ANPC1 | |
| SCHEMBL8740407 | 0.73 | ALDH1A1 (0.60) | KDM4EALDH1A1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065291-A | Herbicidal 1-(2-hydroxymethylpyrrolidinyl) carboxanilides | CHEVRON RESEARCH COMPANY (US) | 1977-12-27 | — | — | US | disclosed |