Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10715386 | 0.99 | ALDH1A1 (0.59) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL31234028 | 0.83 | SMN1; SMN2 (0.67) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL13074405 | 0.80 | ALDH1A1 (0.69) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL25668727 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL25668731 | 0.78 | TSHR (0.56) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL6852416 | 0.76 | KDM4E (0.62) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL9188898 | 0.75 | FAAH (0.62) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14413907 | 0.75 | EPHX2 (0.73) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL830749 | 0.75 | RAB9A (0.64) | ALDH1A1HPGDTSHRSMN1; SMN2MEN1 | |
| SCHEMBL7112664 | 0.74 | ALDH1A1 (0.57) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642587-A4 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA. | UNIV MICHIGAN (US) | 1997-03-19 | — | — | EP | claimed |
| EP-0642587-A1 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA | THE UNIVERSITY OF MICHIGAN (US) | 1995-03-15 | — | — | EP | claimed |
| WO-1993024651-A1 | SYSTEM FOR MEASURING PROTEOLYTIC ACTIVITY OF PERIODONTOPATHOGENIC BACTERIA | UNIVERSITY OF MICHIGAN (US) | 1993-12-09 | — | — | WO | claimed |
| US-5116735-A | Colorimetric assay, hydrolysis of chromogen | THE UNIVERSITY OF MICHIGAN (US) | 1992-05-26 | — | — | US | disclosed |