Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | SLC26A4 | O43511 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756334 | 0.84 | HTT (0.57) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL751538 | 0.84 | LMNA (0.62) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL24470810 | 0.81 | LMNA (1.00) | LMNAHTTANO1SLC26A4KMT2A | |
| SCHEMBL29712989 | 0.81 | LMNA (1.00) | LMNAHTTANO1SLC26A4KMT2A | |
| SCHEMBL756497 | 0.81 | LMNA (0.51) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL765549 | 0.79 | ANO1 (0.52) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL754620 | 0.79 | ANO1 (0.48) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL3221505 | 0.75 | LMNA (0.60) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL3225947 | 0.75 | LMNA (0.57) | LMNAHTTMAOBACHEANO1 | |
| SCHEMBL6593795 | 0.73 | MAOB (0.55) | LMNAHTTMAOBACHEANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042894-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2016-07-13 | — | — | EP | disclosed |
| EP-2181985-B1 | Antiviral Agent | SHIONOGI & CO (JP) | 2011-10-26 | — | — | EP | disclosed |
| EP-2181985-A1 | Antiviral Agent | SHIONOGI & CO., LTD. (JP) | 2010-05-05 | — | — | EP | disclosed |