SCHEMBL756334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751538	0.86	LMNA (0.62)	HTTLMNAANO1MAOBACHE
	SCHEMBL12207267	0.84	LMNA (0.68)	HTTLMNAANO1MAOBACHE
	SCHEMBL754592	0.80	MEN1 (0.56)	HTTLMNAMAOBMAPTMAOA
	SCHEMBL717067	0.76	KDM4E (0.62)	MAOBMAPTKDM4EKMT2AALDH1A1
	SCHEMBL3221505	0.76	LMNA (0.60)	HTTLMNAANO1MAOBACHE
	SCHEMBL3225947	0.76	LMNA (0.57)	HTTLMNAANO1MAOBACHE
	SCHEMBL756497	0.75	LMNA (0.51)	HTTLMNAANO1MAOBACHE
	SCHEMBL24470810	0.73	LMNA (1.00)	HTTLMNAANO1KMT2AMEN1
	SCHEMBL29712989	0.73	LMNA (1.00)	HTTLMNAANO1KMT2AMEN1
	SCHEMBL765549	0.73	ANO1 (0.52)	HTTLMNAANO1MAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.