SCHEMBL751538

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL756334	0.86	HTT (0.57)	LMNAHTTANO1SLC16A3MAOB
	SCHEMBL12207267	0.84	LMNA (0.68)	LMNAHTTANO1SLC16A3MAOB
	SCHEMBL3221505	0.83	LMNA (0.60)	LMNAHTTANO1SLC16A3MAOB
	SCHEMBL3225947	0.80	LMNA (0.57)	LMNAHTTANO1SLC16A3MAOB
	SCHEMBL24470810	0.77	LMNA (1.00)	LMNAHTTANO1SLC26A4KMT2A
	SCHEMBL29712989	0.77	LMNA (1.00)	LMNAHTTANO1SLC26A4KMT2A
	SCHEMBL754620	0.77	ANO1 (0.48)	LMNAHTTANO1SLC16A3MAOB
	SCHEMBL765549	0.77	ANO1 (0.52)	LMNAHTTANO1MAOBMAOA
	SCHEMBL756497	0.74	LMNA (0.51)	LMNAHTTANO1MAOBMAOA
	SCHEMBL26106454	0.71	SLC16A3 (0.60)	LMNAHTTSLC16A3MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.