Pinadoline

Pinadoline

SCHEMBL122117

O=C(CCCCCl)NNC(=O)N1Cc2ccccc2Oc2ccc(Cl)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 4/20 1.00
PTGER1 P34995 8/20 0.72
MAPT P10636 2/20 0.70
MEN1 O00255 1/20 0.70
ALDH1A1 P00352 1/20 0.70
CYP1A2 P05177 1/20 0.70
CYP3A4 P08684 1/20 0.70
CYP2D6 P10635 1/20 0.70
ALOX15 P16050 1/20 0.70
CYP2C19 P33261 1/20 0.70
THPO P40225 1/20 0.70
PMP22 Q01453 1/20 0.70
KMT2A Q03164 1/20 0.70
HDAC3 O15379 1/20 0.45
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
HDAC4 P56524 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pinadoline SCHEMBL29837240 1.00 PTGER2 (1.00) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11831961 0.99 PTGER2 (0.98) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11829581 0.97 PTGER2 (0.94) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11831447 0.91 PTGER2 (0.84) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11538739 0.91 PTGER2 (0.84) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11838222 0.90 PTGER2 (0.82) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11836026 0.90 PTGER2 (0.82) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11835999 0.90 PTGER2 (0.82) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL11825745 0.90 PTGER2 (0.82) PTGER2PTGER1MAPTMEN1ALDH1A1
SCHEMBL9857510 0.89 PTGER2 (0.80) PTGER2PTGER1MAPTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 472 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-4719353-A1 REVERSIBLE SURFACTANT AND MULTIFUNCTIONAL DRUG DELIVERY SYSTEMS BASED THEREON Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-04-08 EP disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed
US-4170593-A ANTIINFLAMMATORY, ANTIDIARRHEA G. D. SEARLE & CO. (US) 1979-10-09 US disclosed
US-4125532-A ANTIINFLAMMATORY, ANTIDIARRHEA G. D. SEARLE & CO. (US) 1978-11-14 US disclosed
US-4045442-A ANTIINFLAMMATORY, ANTIDIARRHEA G. D. SEARLE & CO. (US) 1977-08-30 US disclosed
US-3992375-A Dibenzoxazepine N-carboxylic acid hydrazines and derivatives G. D. SEARLE & CO. (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A PTGER2 3011/4885PTGER1 3880/4885MAPT 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.