Fluorotryptophane

Fluorotryptophane

SCHEMBL122142

N[C@@H](Cc1c[nH]c2ccc(F)cc12)C(=O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.73
KMT2A Q03164 4/20 0.73
TSHR P16473 3/20 0.73
SLC6A4 P31645 3/20 0.73
KDM4E B2RXH2 2/20 0.73
LMNA P02545 2/20 0.73
MAPT P10636 2/20 0.73
HTR2C P28335 2/20 0.73
BLM P54132 2/20 0.73
PMP22 Q01453 2/20 0.73
HTR1A P08908 2/20 0.73
ALDH1A1 P00352 1/20 0.73
CYP3A4 P08684 1/20 0.73
ADORA3 P0DMS8 1/20 0.73
ALOX15 P16050 1/20 0.73
NFKB1 P19838 1/20 0.73
HTR7 P34969 1/20 0.73
HTR2B P41595 1/20 0.73
MTOR P42345 1/20 0.73
NPSR1 Q6W5P4 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorotryptophane SCHEMBL125000 1.00 HTR2A (0.73) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL29623254 1.00 HTR2A (0.73) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL29623154 1.00 HTR2A (0.73) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL29358068 1.00 HTR2A (0.73) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL249955 1.00 HTR2A (0.73) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL18301531 0.94 KMT2A (0.78) HTR2AKMT2ATSHRSLC6A4KDM4E
Fluorotryptophane SCHEMBL18301535 0.94 KMT2A (0.78) HTR2AKMT2ATSHRSLC6A4KDM4E
SCHEMBL248870 0.89 KMT2A (0.66) HTR2AKMT2ATSHRSLC6A4KDM4E
SCHEMBL2330930 0.89 KMT2A (0.66) HTR2AKMT2ATSHRSLC6A4KDM4E
SCHEMBL7331236 0.89 HTR2A (0.66) HTR2AKMT2ATSHRSLC6A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2522 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
EP-3746467-B1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI SA (FR) 2025-10-08 EP claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 WO claimed
US-20250130224-A1 PHOTOREACTIVE ANTIBODY BINDING DOMAINS WITH EPITOPE TAGS FOR MULTIPLEXED ANTIBODY LABELING, DETECTION, AND PURIFICATION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2025-04-24 US claimed
CN-119613495-A C3 complement inhibition polypeptide, preparation method and medical application thereof 远森制药(杭州)有限公司 2025-03-14 CN claimed
CN-119158034-A Bicyclic peptide ligands specific for conjugated protein-4 拜斯科技术开发有限公司 2024-12-20 CN claimed
US-20240400638-A1 COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS MAGNI GUIDO (CH) 2024-12-05 US claimed
EP-4464715-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 BicycleTx Limited (GB) 2024-11-20 EP claimed
EP-4274838-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LTD (GB) 2024-09-25 EP claimed
US-5017481-A Biosynthesis AJINOMOTO CO., INC. (JP) 1991-05-21 US claimed
EP-0203031-A2 Biologically active lysine containing octapeptides The Administrators of The Tulane University Educational Fund (US) 1986-11-26 EP claimed
EP-0081107-B1 PROCESS FOR PRODUCING L-TRYPTOPHAN BY FERMENTATION AJINOMOTO CO., INC. (JP) 1986-09-10 EP claimed
EP-0183006-A2 A recombinant DNA-molecule, coryneform bacteria carrying recombinant DNA and process for producing an aromatic amino acid by using the same AJINOMOTO CO., INC. (JP) 1986-06-04 EP claimed
US-4560652-A BACILLUS MUTANT AZASERINE, METHYL-TRYPTOPHAN AND FLUORO-TRYPTOPHAN RESISTANT; FEEDS AJINOMOTO CO., INC. (JP) 1985-12-24 US claimed
EP-0081107-A2 Process for producing L-tryptophan by fermentation AJINOMOTO CO., INC. (JP) 1983-06-15 EP claimed
EP-0080378-A2 L-tryptophan-producing microorganisms AJINOMOTO CO., INC. (JP) 1983-06-01 EP claimed
US-4371614-A E.Coli bacteria carrying recombinant plasmids and their use in the fermentative production of L-tryptophan AJINOMOTO CO., INC. (JP) 1983-02-01 US claimed
US-4363875-A Process for producing L-tryptophan, and a pure culture of a microorganism strain used in said process SHOWA DENKO K.K. (JP) 1982-12-14 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed