Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | HTR7 | P34969 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | MTOR | P42345 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorotryptophane SCHEMBL125000 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL29623254 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL29358068 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL122142 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL249955 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL18301531 | 0.94 | KMT2A (0.78) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL18301535 | 0.94 | KMT2A (0.78) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL248870 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL2330930 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL7331236 | 0.89 | HTR2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-12448398-B2 | Semi-synthetic analogues of epipolythiodioxopiperazine alkaloids | OHIO STATE INNOVATION FOUNDATION (US) | 2025-10-21 | — | — | US | disclosed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| US-20220235072-A1 | SEMI-SYNTHETIC ANALOGUES OF EPIPOLYTHIODIOXOPIPERAZINE ALKALOIDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-07-28 | — | — | US | disclosed |
| EP-3986414-A1 | SEMI-SYNTHETIC ANALOGUES OF EPIPOLYTHIODIOXOPIPERAZINE ALKALOIDS | Ohio State Innovation Foundation (US) | 2022-04-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448398-B2 | Semi-synthetic analogues of epipolythiodioxopiperazine alkaloids | EHMT1, EHMT2, KMT5A | HTR2A 2577/4885KMT2A 7/4885TSHR 4178/4885 |
| US-20220235072-A1 | SEMI-SYNTHETIC ANALOGUES OF EPIPOLYTHIODIOXOPIPERAZINE ALKALOIDS | EHMT1, EHMT2, KMT5A | HTR2A 2577/4885KMT2A 7/4885TSHR 4178/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | HTR2A 2719/4885KMT2A 3415/4885TSHR 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.