Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | BLM | P54132 | 2/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | HTR7 | P34969 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | MTOR | P42345 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorotryptophane SCHEMBL125000 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL29623254 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL29623154 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL29358068 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL122142 | 1.00 | HTR2A (0.73) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL18301531 | 0.94 | KMT2A (0.78) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| Fluorotryptophane SCHEMBL18301535 | 0.94 | KMT2A (0.78) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL248870 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL2330930 | 0.89 | KMT2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E | |
| SCHEMBL7331236 | 0.89 | HTR2A (0.66) | HTR2AKMT2ATSHRSLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108315370-A | A kind of preparation method of halogen tryptophan | 滨海吉尔多肽有限公司 | 2018-07-24 | — | — | CN | claimed |
| EP-0017760-B1 | SOMATOSTATIN ANALOG PEPTIDES, THEIR PREPARATION AND USE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION | CIBA-GEIGY AG (CH) | 1983-05-11 | — | — | EP | claimed |
| US-4316890-A | Peptides and processes for the manufacture thereof | CIBA-GEIGY CORPORATION (US) | 1982-02-23 | — | — | US | claimed |
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| CN-106188239-B | Potent compstatin analogs | 宾夕法尼亚州大学理事会 | 2020-01-07 | — | — | CN | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
| US-20190016758-A1 | Potent Compstatin Analogs | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-01-17 | — | — | US | disclosed |
| EP-3363810-A1 | POTENT COMPSTATIN ANALOGS | The Trustees Of The University Of Pennsylvania (US) | 2018-08-22 | — | — | EP | disclosed |
| CN-108315370-A | A kind of preparation method of halogen tryptophan | 滨海吉尔多肽有限公司 | 2018-07-24 | — | — | CN | disclosed |
| EP-2377877-B1 | Potent compstatin analogs | UNIV PENNSYLVANIA (US) | 2018-03-28 | — | — | EP | disclosed |
| EP-2377878-B1 | Potent compstatin analogs | UNIV PENNSYLVANIA (US) | 2018-03-28 | — | — | EP | disclosed |
| EP-1392317-A4 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA INC (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1392317-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | Antexpharma, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100327-A2 | SUBSTITUTED 1-BENZAZEPINES AND DERIVATIVES THEREOF | ANTEXPHARMA, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-4603120-A | ANTIDIZBETIC, HEMOSATATIC, SOMATOSTATIN ANALOGS | CIBA-GEIGY CORPORATION (US) | 1986-07-29 | — | — | US | disclosed |
| US-4358439-A | ANTIDIABETIC AGENT AND/OR GASTROINTESTINAL BLEEDING | CIBA-GEIGY CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |
| EP-0001295-B1 | SOMATOSTATIN-LIKE CYCLOPEPTIDES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTICAL APPLICATION | CIBA-GEIGY AG (CH) | 1982-03-17 | — | — | EP | disclosed |
| US-4316890-A | Peptides and processes for the manufacture thereof | CIBA-GEIGY CORPORATION (US) | 1982-02-23 | — | — | US | disclosed |
| US-4238481-A | HYPOGLYCEMIC AGENT; HYPERGLYCEMIC AGENT; ANIMAL GROWTH REGULATOR | CIBA-GEIGY CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| EP-0001295-A2 | Somatostatin-like cyclopeptides, a process for their preparation, pharmaceutical compositions containing them, and their therapeutical application | CIBA-GEIGY AG (CH) | 1979-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | HTR2A 3134/4885KMT2A 2510/4885TSHR 2337/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | HTR2A 3059/4885KMT2A 2475/4885TSHR 2183/4885 |
| US-20190016758-A1 | Potent Compstatin Analogs | C3AR1, C9, C1QBP | HTR2A 3106/4885KMT2A 4236/4885TSHR 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.