SCHEMBL2330930

SCHEMBL2330930

N[C@@H](Cc1c[nH]c2cc(F)ccc12)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.66
▸ TSHR P16473 3/20 0.66
▸ KDM4E B2RXH2 3/20 0.66
▸ LMNA P02545 3/20 0.66
▸ MAPT P10636 3/20 0.66
▸ BLM P54132 3/20 0.66
▸ PMP22 Q01453 3/20 0.66
▸ MEN1 O00255 3/20 0.66
▸ HIF1A Q16665 2/20 0.66
▸ MPO P05164 2/20 0.66
▸ PTPRA P18433 1/20 0.65
▸ CYP2C19 P33261 1/20 0.62
▸ HTR2A P28223 4/20 0.61
▸ HTR2C P28335 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ CYP3A4 P08684 2/20 0.61
▸ ALOX15 P16050 2/20 0.61
▸ NFKB1 P19838 2/20 0.61
▸ NPSR1 Q6W5P4 2/20 0.61
▸ HSD17B10 Q99714 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18029199 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL30381733 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL120340 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL7096864 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL248870 1.00 KMT2A (0.66) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262937 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
SCHEMBL4262934 0.89 HTR2A (0.60) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29358068 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL29623154 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT
Fluorotryptophane SCHEMBL125000 0.89 HTR2A (0.73) KMT2ATSHRKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094701-A TLR3 binding bicyclic peptide ligands — 2026-05-26 — — CN claimed
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF ALPHA 9 ONCOLOGY INC (CA) 2026-03-19 — — US claimed
US-20250361273-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC 2025-11-27 — — US claimed
WO-2025245483-A1 METHODS AND COMPOSITIONS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-11-27 — — WO claimed
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-06-19 — — US claimed
US-12319946-B2 Methods for producing modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-06-03 — — US claimed
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2025-05-15 — — US claimed
WO-2025099047-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1) BICYCLETX LIMITED (GB) 2025-05-15 — — WO claimed
WO-2025054727-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2025-03-20 — — WO claimed
WO-2025046244-A1 TLR3 BINDING BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2025-03-06 — — WO claimed
CN-117337295-A Bicyclic peptide ligands specific for TREM2 拜斯科技术开发有限公司 2024-01-02 — — CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 — — EP claimed
WO-2023178449-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-09-28 — — WO claimed
US-20230287466-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH (US) 2023-09-14 — — US claimed
WO-2023099669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2023-06-08 — — WO claimed
US-11591627-B2 Modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-02-28 — — US claimed
WO-2022195287-A9 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-10-20 — — WO claimed
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-09-22 — — US claimed
WO-2022195287-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 BICYCLETX LIMITED (GB) 2022-09-22 — — WO claimed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220296726-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 APP, TIMCC, ADM2 KMT2A 3481/4885TSHR 2889/4885KDM4E 4811/4885
US-20250361273-A1 METHODS AND COMPOSITIONS MC4R, GPR119, MC2R KMT2A 3419/4885TSHR 120/4885KDM4E 2986/4885
US-20250195702-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS GRPR, NPY5R, NPY2R KMT2A 1870/4885TSHR 77/4885KDM4E 2440/4885
US-20260077073-A1 GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR)-TARGETED COMPOUNDS AND USES THEREOF GRPR, GIPR, GLP1R KMT2A 4091/4885TSHR 53/4885KDM4E 4638/4885
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL1RN, IL33 KMT2A 4359/4885TSHR 769/4885KDM4E 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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