Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.33 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220351 | 0.91 | CHRM4 (0.46) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8220211 | 0.91 | ADAM17 (0.48) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8273348 | 0.81 | ADAM17 (0.53) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8221438 | 0.81 | ADAM17 (0.53) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8213698 | 0.80 | ADAM17 (0.53) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8221453 | 0.79 | ADAM17 (0.53) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8414544 | 0.79 | ADAM17 (0.46) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8417459 | 0.79 | ADAM17 (0.47) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL16357752 | 0.79 | CHRM4 (0.46) | CHRM4ADAM17FFAR4DPP4DPP8 | |
| SCHEMBL8274678 | 0.77 | ADAM17 (0.39) | CHRM4ADAM17RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039467-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-8039467-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2011-10-18 | — | — | US | disclosed |
| US-20100145048-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-20100145048-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145048-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TNF, MMP12, MMP8 | CHRM4 4358/4885ADAM17 7/4885FFAR4 1427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.