SCHEMBL12216914

SCHEMBL12216914

CCCCC/C=C\C/C=C\CCCCCCCCC1(CCCCCCCC/C=C\C/C=C\CCCCC)OCC(CO)CO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
F7 P08709 3/20 0.41
F3 P13726 3/20 0.41
PPARG P37231 2/20 0.41
PPARD Q03181 2/20 0.41
PPARA Q07869 2/20 0.41
DUSP3 P51452 1/20 0.41
PTPN7 P35236 1/20 0.41
FFAR1 O14842 1/20 0.41
LMNA P02545 1/20 0.41
FABP3 P05413 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP19A1 P11511 1/20 0.41
FABP4 P15090 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
PTGS1 P23219 1/20 0.41
GNA15 P30679 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12216913 0.89 TRPV1 (0.40) ALDH1A1KDM4EF7F3PPARG
SCHEMBL15800641 0.84 FAAH (0.40) ALDH1A1DUSP3HPGD
SCHEMBL246601 0.84 TRPV1 (0.36) ALDH1A1KDM4EF7F3PPARG
SCHEMBL22838309 0.84 TRPV1 (0.36) ALDH1A1KDM4EF7F3PPARG
SCHEMBL22838284 0.83 TRPV1 (0.36) ALDH1A1KDM4EF7F3PPARG
SCHEMBL30446077 0.82 FAAH (0.40) ALDH1A1KDM4EPPARGPPARDPPARA
SCHEMBL22838307 0.82 FAAH (0.37)
SCHEMBL19882101 0.82 CNR1 (0.35) ALDH1A1KDM4EF7F3PPARG
SCHEMBL2332115 0.82 CNR1 (0.35) ALDH1A1KDM4EF7F3PPARG
SCHEMBL25067336 0.81 FAAH (0.41) ALDH1A1KDM4EF7F3PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4495237-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2026-05-13 EP disclosed
US-12453776-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2025-10-28 US disclosed
EP-4495237-A2 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2025-01-22 EP disclosed
US-20240424105-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-12-26 US disclosed
EP-4241767-B1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORP (CA) 2024-10-23 EP disclosed
US-12042541-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2024-07-23 US disclosed
US-20240042039-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-02-08 US disclosed
EP-4241767-A2 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS Arbutus Biopharma Corporation (CA) 2023-09-13 EP disclosed
US-11712476-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-01 US disclosed
US-11712476-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-01 US disclosed
US-9139554-B2 Amino lipids and methods for the delivery of nucleic acids TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2015-09-22 US disclosed
US-9139554-B2 Amino lipids and methods for the delivery of nucleic acids TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2015-09-22 US disclosed
EP-2350043-B9 IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS TEKMIRA PHARMACEUTICALS CORP (CA) 2014-08-20 EP disclosed
EP-2350043-B1 IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS TEKMIRA PHARMACEUTICALS CORP (CA) 2014-03-26 EP disclosed
US-20110311582-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2011-12-22 US disclosed
US-20110311582-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (CA) 2011-12-22 US disclosed
US-20110256175-A1 AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-10-20 US disclosed
US-20110256175-A1 AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-10-20 US disclosed
WO-2010054401-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ALNYLAM PHARMACEUTICALS, INC. (US) 2010-05-14 WO disclosed
WO-2010042877-A1 IMPROVED AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12453776-B2 Lipids and compositions for the delivery of therapeutics PHOSPHO1, MBOAT1, SGMS1 ALDH1A1 2999/4885KDM4E 1867/4885F7 2967/4885
US-20240424105-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS PHOSPHO1, MBOAT1, SGMS1 ALDH1A1 3640/4885KDM4E 1963/4885F7 3390/4885
US-12042541-B2 Lipids and compositions for the delivery of therapeutics PHOSPHO1, MBOAT1, SGMS1 ALDH1A1 2999/4885KDM4E 1867/4885F7 2967/4885
US-11712476-B2 Lipids and compositions for the delivery of therapeutics SGMS2, APOB, PHOSPHO1 ALDH1A1 4140/4885KDM4E 1410/4885F7 977/4885
US-20240042039-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS PHOSPHO1, MBOAT1, SGMS1 ALDH1A1 2999/4885KDM4E 1867/4885F7 2967/4885
US-20110311582-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS APOB, LPAR3, LPAR2 ALDH1A1 4355/4885KDM4E 1001/4885F7 1596/4885
US-20110256175-A1 AMINO LIPIDS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS NSUN3, SARNP, LDLR ALDH1A1 4284/4885KDM4E 3120/4885F7 4411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.