Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.85 |
| ▸ | AR | P10275 | 3/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.85 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.79 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4290159 | 1.00 | PGR (0.85) | PGRARCHRM1NR3C2NR3C1 | |
| Hydrocortisone Probutate SCHEMBL30507561 | 0.97 | PGR (0.82) | PGRARCHRM1NR3C2NR3C1 | |
| Hydrocortisone Probutate SCHEMBL14339602 | 0.97 | PGR (0.82) | PGRARCHRM1NR3C2NR3C1 | |
| Hydrocortisone Probutate SCHEMBL4778 | 0.97 | PGR (0.82) | PGRARCHRM1NR3C2NR3C1 | |
| Hydrocortisone Probutate SCHEMBL4290122 | 0.97 | PGR (0.82) | PGRARCHRM1NR3C2NR3C1 | |
| Hydrocortisone Probutate SCHEMBL4280673 | 0.97 | PGR (0.82) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL605474 | 0.97 | NR3C2 (0.85) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL4278627 | 0.95 | PGR (0.91) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL17219849 | 0.94 | PGR (0.80) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL604267 | 0.94 | PGR (0.80) | PGRARCHRM1NR3C2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 613 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744657-A1 | THERAPEUTIC AGENT FOR HUMAN GRAFT VERSUS HOST DISEASE AND COMBINATION THEREOF | National University Corporation Okayama University (JP) | 2026-05-20 | — | — | EP | claimed |
| WO-2023160631-A1 | NANO PREPARATION FOR JOINT ANALGESIA, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中南大学湘雅医院 | 2023-08-31 | — | — | WO | claimed |
| CN-116077465-A | Nanometer preparation for joint pain relief, and preparation method and application thereof | 中南大学湘雅医院 | 2023-05-09 | — | — | CN | claimed |
| US-11376262-B2 | Method of treating an inflammatory or infectious disease | ACTIVUS PHARMA CO., LTD. (JP) | 2022-07-05 | — | — | US | claimed |
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | claimed |
| US-20200129526-A1 | METHOD OF TREATING AN INFLAMMATORY OR INFECTIOUS DISEASE | FORMOSA PHARMACEUTICALS, INC. (TW) | 2020-04-30 | — | — | US | claimed |
| CN-110945016-A | Peptide compounds, conjugate compounds and uses thereof for the treatment of inflammatory diseases | 特拉斯福特普拉斯公司 | 2020-03-31 | — | — | CN | claimed |
| US-10588913-B2 | Aqueous suspension agent containing glucocorticosteroid nanoparticles | ACTIVUS PHARMA CO., LTD. (JP) | 2020-03-17 | — | — | US | claimed |
| US-20180117064-A1 | AQUEOUS SUSPENSION AGENT CONTAINING GLUCOCORTICOSTEROID NANOPARTICLES | FORMOSA PHARMACEUTICALS, INC. (TW) | 2018-05-03 | — | — | US | claimed |
| EP-3295943-A1 | AQUEOUS SUSPENSION AGENT COMPRISING GLUCOCORTICOSTEROID NANOPARTICLES | Activus Pharma Co., Ltd. (JP) | 2018-03-21 | — | — | EP | claimed |
| EP-2050439-B1 | PROCESS FOR PRODUCTION OF SPHERICAL GRANULE CONTAINING SLIGHTLY WATER-SOLUBLE SUBSTANCE | ASAHI CHEMICAL IND (JP) | 2016-11-23 | — | — | EP | claimed |
| US-9095512-B2 | Method for producing spherical base granules comprising hardly water-soluble drug | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-08-04 | — | — | US | claimed |
| US-20090012051-A1 | EXTERNAL PREPARATION | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-01-08 | — | — | US | claimed |
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-12-13 | — | — | US | claimed |
| EP-1810692-A1 | REMEDIES/PREVENTIVES FOR CHRONIC SKIN DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-07-25 | — | — | EP | claimed |
| WO-1997027862-A1 | SUPPLEMENTATION OF GLUCOCORTICOIDS | BELLARA MEDICAL PRODUCTS LIMITED (AU) | 1997-08-07 | — | — | WO | claimed |
| US-4794107-A | HYDROCORTISONE BUTYRATE PROPIONATE, PROPYLENE GLYCOL, SURFACTANTS, PARAFIN HYDROCARBONS; ANTIINFLAMMATORY AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | claimed |
| US-4794106-A | HYDROCORTISONE BUTYRATE PROPIONATE, HIGHER PARAFFINIC HYDROCARBON, SURFACTANT | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1988-12-27 | — | — | US | claimed |
| JP-61167614-A | — | — | None | — | — | JP | disclosed |
| JP-S59137408-A | OINTMENT | TAISHO PHARMACEUT CO LTD | 1984-08-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012051-A1 | EXTERNAL PREPARATION | CYP4A11, CYP46A1, CYP11B2 | PGR 2297/4885AR 2683/4885CHRM1 2397/4885 |
| US-20070287689-A1 | Therapeutic And/Or Preventive Agents For Chronic Skin Diseases | PDE4A, PDE3B, PDE2A | PGR 1575/4885AR 1114/4885CHRM1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.