Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148537 | 0.90 | L3MBTL1 (0.41) | L3MBTL1GAAMAOBMAPTPOLB | |
| SCHEMBL7640912 | 0.88 | PARP10 (0.43) | L3MBTL1GAAMAOBMAPTPOLB | |
| SCHEMBL104000 | 0.86 | KMT2A (0.52) | L3MBTL1MAPTLMNAPRSS1PARP10 | |
| SCHEMBL9312577 | 0.84 | NQO1 (0.61) | L3MBTL1MAOBMAPTLMNANPSR1 | |
| SCHEMBL11019446 | 0.83 | L3MBTL1 (0.42) | L3MBTL1GAAMAOBMAPTPOLB | |
| SCHEMBL18905505 | 0.83 | L3MBTL1 (0.42) | L3MBTL1GAAMAOBMAPTPOLB | |
| SCHEMBL7457274 | 0.81 | NR1I2 (0.61) | L3MBTL1GAAMAPTPOLBAPEX1 | |
| SCHEMBL5033226 | 0.81 | GAA (0.56) | L3MBTL1GAAMAPTLMNAALDH1A1 | |
| SCHEMBL21914622 | 0.81 | LSS (0.43) | L3MBTL1GAAMAOBMAPTPOLB | |
| SCHEMBL9551255 | 0.81 | MAOB (0.64) | L3MBTL1MAOBMAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8043534-B2 | An adhesive comprising a maleimide and an aromatic diene or an aromatic monoene which cure to form useful thermosetting resins for the microelectronic packaging industry; semiconcuctor dies; addition polymerization/Diels-Alder reaction; heat and acid resistance; toughness; noncracking; nondestructive | DESIGNER MOLECULES, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8043534-B2 | An adhesive comprising a maleimide and an aromatic diene or an aromatic monoene which cure to form useful thermosetting resins for the microelectronic packaging industry; semiconcuctor dies; addition polymerization/Diels-Alder reaction; heat and acid resistance; toughness; noncracking; nondestructive | DESIGNER MOLECULES, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080075965-A1 | Maleimide compositions and methods for use thereof | KDM4E, MLLT1, DOT1L | L3MBTL1 2886/4885GAA 2058/4885MAOB 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.