SCHEMBL7640912

SCHEMBL7640912

C=C(C)c1ccc(OCOCC)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
NQO1 P15559 1/20 0.43
ALDH1A1 P00352 2/20 0.41
NPC1 O15118 2/20 0.41
PLK1 P53350 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.39
THRA P10827 1/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
PLA2G4B P0C869 1/20 0.39
NR1I2 O75469 1/20 0.38
RAB9A P51151 1/20 0.38
MAOB P27338 1/20 0.38
LTA4H P09960 1/20 0.37
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12227199 0.88 L3MBTL1 (0.45) PARP10PRSS1PRSS2PRSS3NQO1
SCHEMBL9312577 0.86 NQO1 (0.61) PARP10PRSS1PRSS2PRSS3NQO1
SCHEMBL148537 0.82 L3MBTL1 (0.41) PARP10PRSS1PRSS2PRSS3L3MBTL1
SCHEMBL7638019 0.81 KMT2A (0.43) PRSS1PRSS2PRSS3ALDH1A1L3MBTL1
SCHEMBL8751807 0.81 NQO1 (0.63) PARP10PRSS1PRSS2PRSS3NQO1
SCHEMBL8829481 0.81 NQO1 (0.54) PARP10PRSS1PRSS2PRSS3NQO1
SCHEMBL9331132 0.81 L3MBTL1 (0.63) PARP10ALDH1A1L3MBTL1GAANPSR1
SCHEMBL5033226 0.78 GAA (0.56) ALDH1A1NPC1L3MBTL1GAAKMT2A
SCHEMBL9781935 0.78 L3MBTL1 (0.56) PLK1L3MBTL1GAAKMT2APLA2G4B
SCHEMBL4544518 0.77 NQO1 (0.52) NQO1L3MBTL1KMT2ARAB9AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6465150-B1 COMPRISING AN AROMATIC SULFONIC ACID ONIUM SALT COMPOUND ACID GENERATOR, FOR EXAMPLE, 2,4-DIFLUOROBENZENESULFONIC ACID ANION AND AN ONIUM CATION OF SULFUR OR IODONIUM, AND A COPOLYMER REPRESENTED BY 4-HYDROXYSTYRENE/4-T-BUTOXYSTYRENE COPOLYMER JSR CORPORATION (JP) 2002-10-15 US claimed
US-20180024433-A1 RESIST COMPOSITION, METHOD FOR FORMING RESIST PATTERN, AND POLYMER COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2018-01-25 US disclosed
US-20180022916-A1 METHOD OF PREPARING POLYMER COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2018-01-25 US disclosed
US-6465150-B1 COMPRISING AN AROMATIC SULFONIC ACID ONIUM SALT COMPOUND ACID GENERATOR, FOR EXAMPLE, 2,4-DIFLUOROBENZENESULFONIC ACID ANION AND AN ONIUM CATION OF SULFUR OR IODONIUM, AND A COPOLYMER REPRESENTED BY 4-HYDROXYSTYRENE/4-T-BUTOXYSTYRENE COPOLYMER JSR CORPORATION (JP) 2002-10-15 US disclosed
EP-0220831-B1 Styryloxy resins and polymerization process LOCTITE IRELAND LTD (IE) 1994-04-20 EP disclosed
EP-0165769-B1 POLYFUNCTIONAL STYRYLOXY COMPOUNDS AND METHOD OF FORMING A CROSS-LINKED POLYMER LOCTITE (IRELAND) Ltd. (IE) 1991-08-21 EP disclosed
US-4732956-A Styryloxy resins and compositions thereof LOCTITE (IRELAND) LTD. (IE) 1988-03-22 US disclosed
EP-0220831-A2 Styryloxy resins and polymerization process LOCTITE (IRELAND) Ltd. (IE) 1987-05-06 EP disclosed
US-4543397-A PERMANENT COLORATION IN CURED PRODUCTS LOCTITE (IRELAND) LTD. (IE) 1985-09-24 US disclosed