Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP8 | P40818 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12253692 | 0.85 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16226306 | 0.82 | ELANE (0.61) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1340134 | 0.77 | AOC3 (0.53) | SMN1; SMN2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL28168314 | 0.77 | LCK (0.47) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31441200 | 0.76 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28168311 | 0.75 | ELANE (0.53) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28407481 | 0.75 | EPHX2 (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL496978 | 0.73 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18189126 | 0.72 | KDM4E (0.44) | SMN1; SMN2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL16226288 | 0.72 | EPHX2 (0.54) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8502401-B2 | Polymeric compositions comprising per(phenylethynyl) arene derivatives | Delsper LP (US) | 2013-08-06 | — | — | US | disclosed |
| US-8373287-B2 | — | — | 2013-02-12 | — | — | US | disclosed |
| US-20110260343-A1 | POLYMERIC COMPOSITIONS COMPRISING PER(PHENYLETHYNYL) ARENE DERIVATIVES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-10-27 | — | — | US | disclosed |