SCHEMBL496978

SCHEMBL496978

COc1ccc2c(c1OC)C(=O)c1ccccc1C2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
NPC1 O15118 2/20 1.00
MAPT P10636 8/20 0.68
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
ALDH1A1 P00352 7/20 0.67
KDM4E B2RXH2 2/20 0.67
TDP1 Q9NUW8 2/20 0.67
USP2 O75604 1/20 0.67
DUSP3 P51452 1/20 0.67
POLB P06746 3/20 0.56
THRB P10828 2/20 0.56
ADORA2A P29274 2/20 0.56
FGB P02675 1/20 0.56
MAPK1 P28482 1/20 0.56
PPARG P37231 1/20 0.56
NCOA2 Q15596 1/20 0.56
NCOA1 Q15788 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786089 0.93 RAB9A (0.87) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL12253692 0.87 RAB9A (0.76) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL4700188 0.84 RAB9A (0.71) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL5146135 0.82 SMN1; SMN2 (0.69) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL1426442 0.82 SMN1; SMN2 (0.70) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL3419749 0.82 SMN1; SMN2 (0.70) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL29906115 0.82 SMN1; SMN2 (0.70) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL4706459 0.81 RAB9A (0.67) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL9846590 0.81 RAB9A (0.68) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL9751849 0.81 RAB9A (0.68) RAB9ASMN1; SMN2NPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP claimed
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH ZURICH (CH) 2021-06-24 US claimed
CN-108957895-B Acid-base responsive electrochromic film, preparation method and application thereof, and electrochromic device 常州铱视光电科技有限公司 2021-06-11 CN claimed
CN-108873537-B Electrochromic film, preparation method and application thereof, and electrochromic device 常州铱视光电科技有限公司 2021-06-04 CN claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP claimed
US-4278607-A Process for the preparation of dimethoxyanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1981-07-14 US claimed
CN-110520433-B Phosphorus-containing phenol compound, phosphorus-containing epoxy resin, curable resin composition or epoxy resin composition, and cured product thereof 日铁化学材料株式会社 2023-12-05 CN disclosed
US-20230320940-A1 PHOTOCATIONICALLY CURABLE COMPOSITION AND DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORPORATION (JP) 2023-10-12 US disclosed
CN-110951048-B Phosphorus-containing hardener, epoxy resin composition, cured product, prepreg, and laminate 日铁化学材料株式会社 2023-09-29 CN disclosed
EP-4194477-A1 PHOTOCATIONIC CURABLE COMPOSITION AND CURABLE DENTAL COMPOSITION Tokuyama Dental Corporation (JP) 2023-06-14 EP disclosed
CN-110194843-B Phosphorus-containing phenoxy resin, resin composition, material for circuit board, and cured product 日铁化学材料株式会社 2023-01-03 CN disclosed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP disclosed
CN-113750197-A Traditional Chinese medicine composition for controlling blood sugar, capsule and preparation method of capsule 珠海中科先进技术研究院有限公司 2021-12-07 CN disclosed
US-4278607-A Process for the preparation of dimethoxyanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
US-4278607-A Process for the preparation of dimethoxyanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
EP-0014367-A1 Process for the preparation of dimethoxyanthraquinones BAYER AG (DE) 1980-08-20 EP disclosed
EP-0014367-A1 Process for the preparation of dimethoxyanthraquinones BAYER AG (DE) 1980-08-20 EP disclosed
EP-0014367-A1 Process for the preparation of dimethoxyanthraquinones BAYER AG (DE) 1980-08-20 EP disclosed
US-4080370-A Process for producing high purity methoxyanthraquinones MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JA) 1978-03-21 US disclosed
US-3983145-A Use of alpha-di(lower alkoxy) anthraquinones in the synthesis of Alizarin Saphirols TOMS RIVER CHEMICAL CORPORATION (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320940-A1 PHOTOCATIONICALLY CURABLE COMPOSITION AND DENTAL CURABLE COMPOSITION CTH, GCLC, AAAS RAB9A 2337/4885SMN1; SMN2 3290/4885NPC1 4742/4885
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION TOMM70, TOMM34, TIMM50 RAB9A 3373/4885SMN1; SMN2 4118/4885NPC1 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.