SCHEMBL1340134

SCHEMBL1340134

COc1ccc(CO)c(OC)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.49
POLB P06746 1/20 0.49
CYP1A2 P05177 1/20 0.49
CHRM2 P08172 1/20 0.49
SLC6A4 P31645 1/20 0.49
OPRD1 P41143 1/20 0.49
OPRK1 P41145 1/20 0.49
KDM4E B2RXH2 6/20 0.47
TSHR P16473 1/20 0.47
APOBEC3A P31941 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
PDE4A P27815 1/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
ALDH1A1 P00352 4/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11300908 0.88 AOC3 (0.46) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL30056339 0.88 AOC3 (0.46) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL9723471 0.85 AOC3 (0.41) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL18189126 0.85 KDM4E (0.44) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL7274253 0.84 SLC2A1 (0.45) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL18189127 0.84 KDM4E (0.47) AOC3SMN1; SMN2POLBKDM4EALDH1A1
SCHEMBL697386 0.83 KMT2A (0.48) POLBOPRD1KDM4ETSHRPDE4A
SCHEMBL20147971 0.83 PDCD1 (0.46) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL8910900 0.82 AOC3 (0.56) AOC3SMN1; SMN2POLBCYP1A2CHRM2
SCHEMBL7274336 0.82 PDE4A (0.42) AOC3SMN1; SMN2POLBCYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
CN-121428030-A Preparation method and application of eicosapentaenoic acid-trimethoxybenzyl alcohol ester 马丁·格哈特·班威尔 2026-01-30 CN disclosed
US-20250215037-A1 ELECTROCHEMICALLY-CLEAVABLE LINKERS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-07-03 US disclosed
US-12281134-B2 Electrochemically-cleavable linkers MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-04-22 US disclosed
US-20250115635-A1 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS MICROSOFT TECHNOLOGY LICENSING, LLC 2025-04-10 US disclosed
CN-119775228-A Simple and convenient method for preparing trimetazidine 北京化工大学 2025-04-08 CN disclosed
US-12215121-B2 Linker structures with minimal scar for enzymatic synthesis MICROSOFT TECHNOLOGY LICENSING, LLC (US) 2025-02-04 US disclosed
CN-117964834-A Polyacrylate polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
EP-4272000-A2 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS Microsoft Technology Licensing LLC (US) 2023-11-08 EP disclosed
EP-0109816-A1 N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-05-30 EP disclosed
EP-0109301-A2 7-(S)-acylaminocephalosporin sulfones and process ELI LILLY AND COMPANY (US) 1984-05-23 EP disclosed
EP-0109300-A2 Desacetylcephalosporin sulfones ELI LILLY AND COMPANY (US) 1984-05-23 EP disclosed
US-4436596-A N-Substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process ELI LILLY AND COMPANY (US) 1984-03-13 US disclosed
EP-0093010-A2 Alpha-hydroxyethylphosphinates, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-11-02 EP disclosed
EP-0004881-B1 PROCESS FOR THE PREPARATION OF AROMATIC AND ARALIPHATIC ALDEHYDES BASF Aktiengesellschaft (DE) 1981-10-07 EP disclosed
US-4239702-A REACTING A BENZOIC ACID WITH ETHYL OR ISOBUTYL CHLOROFORMATE, HYDROGENATION, OPTIONAL OXIDATION SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1980-12-16 US disclosed
US-4224254-A OXIDATION OF AROMATIC ALCOHOLS, SILVER CATALYST BASF AKTIENGESELLSCHAFT (DE) 1980-09-23 US disclosed
EP-0004881-A2 Process for the preparation of aromatic and araliphatic aldehydes BASF Aktiengesellschaft (DE) 1979-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115635-A1 LINKER STRUCTURES WITH MINIMAL SCAR FOR ENZYMATIC SYNTHESIS RNGTT, MMP1, UNG AOC3 719/4885SMN1; SMN2 2921/4885POLB 98/4885
US-20250215037-A1 ELECTROCHEMICALLY-CLEAVABLE LINKERS RNGTT, DNPEP, DTYMK AOC3 629/4885SMN1; SMN2 3794/4885POLB 17/4885
US-12281134-B2 Electrochemically-cleavable linkers RNGTT, DNPEP, DTYMK AOC3 629/4885SMN1; SMN2 3794/4885POLB 17/4885
US-12215121-B2 Linker structures with minimal scar for enzymatic synthesis RNGTT, MMP1, UNG AOC3 719/4885SMN1; SMN2 2921/4885POLB 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.