SCHEMBL1223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Butanone SCHEMBL11122	0.87	CACNA1F (0.40)	MEN1KMT2ARAB9ABRD4TDP1
	Cyclohexanone SCHEMBL6726	0.85	TRPV1 (0.36)	MEN1KMT2ARAB9ABRD4EDNRB
	SCHEMBL14789798	0.83	RAB9A (0.40)	MEN1KMT2ARAB9ABRD4TDO2
	SCHEMBL13388	0.81	BRD4 (0.53)	RAB9ABRD4TDO2EDNRBEDNRA
	SCHEMBL13959362	0.81	PTGS2 (0.42)	MEN1KMT2ARAB9ABRD4TDO2
	SCHEMBL27886960	0.81	EDNRB (0.45)	MEN1KMT2ARAB9AEDNRBEDNRA
	SCHEMBL1754692	0.81	BRD4 (0.56)	MEN1KMT2ABRD4TDO2MAPT
	SCHEMBL13959385	0.79	MAPK14 (0.40)	MEN1KMT2ARAB9ABRD4TDO2
	SCHEMBL13959867	0.79	KMT2A (0.47)	MEN1KMT2ARAB9ABRD4MAPT
	SCHEMBL25406124	0.78	MEN1 (0.39)	MEN1KMT2ARAB9ABRD4EDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.