SCHEMBL122307

SCHEMBL122307

OCC(O)C(O)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.54
CYP1A2 P05177 1/20 0.46
EPHX1 P07099 1/20 0.46
TSHR P16473 1/20 0.46
ALPI P09923 1/20 0.43
PKM P14618 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
SLC7A5 Q01650 1/20 0.43
SLC6A2 P23975 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
MAOA P21397 1/20 0.43
SLC6A4 P31645 1/20 0.43
SLC6A3 Q01959 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
CYP2A6 P11509 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
MDM2 Q00987 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2904622 1.00 TRPA1 (0.54) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL16269804 1.00 TRPA1 (0.54) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL5878109 1.00 TRPA1 (0.54) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL4163177 1.00 TRPA1 (0.54) TRPA1CYP1A2EPHX1TSHRALPI
Bicarbonate SCHEMBL17044690 0.94 CYP1A2 (0.52) TRPA1CYP1A2EPHX1ALPIPKM
SCHEMBL108646 0.90 TRPA1 (0.58) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL537721 0.86 TRPA1 (0.50) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL29189650 0.86 TRPA1 (0.50) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL3418072 0.86 TRPA1 (0.50) TRPA1CYP1A2EPHX1TSHRALPI
SCHEMBL30304201 0.85 TDP1 (0.50) TRPA1CYP1A2EPHX1TSHRALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12396941-B2 Cosmetic composition that resists pilling L'OREAL (FR) 2025-08-26 US claimed
US-12303576-B2 Two phase water-based smudge-resistant make-up remover L'OREAL (FR) 2025-05-20 US claimed
US-11819559-B2 Cosmetic compositions comprising an antimicrobial system with reduced eye irritation or discomfort L'OREAL (FR) 2023-11-21 US claimed
EP-4221665-A1 COSMETIC COMPOSITIONS COMPRISING AN ANTIMICROBIAL SYSTEM WITH REDUCED EYE IRRITATION OR DISCOMFORT L'OREAL (FR) 2023-08-09 EP claimed
CN-116367810-A Cosmetic composition comprising an antimicrobial system for reducing eye irritation or discomfort 欧莱雅 2023-06-30 CN claimed
US-11679072-B2 Water-based smudge-resistant make-up remover L'OREAL (FR) 2023-06-20 US claimed
WO-2022072585-A1 COSMETIC COMPOSITIONS COMPRISING AN ANTIMICROBIAL SYSTEM WITH REDUCED EYE IRRITATION OR DISCOMFORT L'OREAL (FR) 2022-04-07 WO claimed
US-20220096345-A1 COSMETIC COMPOSITIONS COMPRISING AN ANTIMICROBIAL SYSTEM WITH REDUCED EYE IRRITATION OR DISCOMFORT L'OREAL (FR) 2022-03-31 US claimed
US-20220062150-A1 WATER-BASED SMUDGE-RESISTANT MAKE-UP REMOVER L'OREAL (FR) 2022-03-03 US claimed
WO-2022047179-A1 WATER-BASED SMUDGE-RESISTANT MAKE-UP REMOVER L'OREAL (FR) 2022-03-03 WO claimed
US-8398762-B2 Pigmented inkjet ink comprising a bleed control agent E I DU PONT DE NEMOURS AND COMPANY (US) 2013-03-19 US claimed
WO-2010111343-A1 PIGMENTED INKJET INK COMPRISING A BLEED CONTROL AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-30 WO claimed
EP-1238649-B1 Hair dye compositions comprising acidic dyes and lactones KAO CORP (JP) 2008-01-09 EP claimed
US-6776803-B2 Hair dye compositions KAO CORPORATION (JP) 2004-08-17 US claimed
US-20030066141-A1 Hair dye compositions KAO CORPORATION (JP) 2003-04-10 US claimed
EP-1238649-A2 Hair dye compositions Kao Corporation (JP) 2002-09-11 EP claimed
US-6248314-B1 Hair dye composition having a particular buffer capacity and containing an alkylene carbonate KAO CORPORATION (JP) 2001-06-19 US claimed
US-6206935-B1 APPLYING BLEACHING AGENTS AND DIRECT DYE KAO CORPORATION (JP) 2001-03-27 US claimed
EP-1022014-A1 Hair dye composition Kao Corporation (JP) 2000-07-26 EP claimed
US-4181545-A POT LIFE OF HYDROXY POLYBUTADIENE UNITED TECHNOLOGIES CORPORATION (US) 1980-01-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220096345-A1 COSMETIC COMPOSITIONS COMPRISING AN ANTIMICROBIAL SYSTEM WITH REDUCED EYE IRRITATION OR DISCOMFORT GK, PIR, LAGE3 TRPA1 132/4885CYP1A2 1464/4885EPHX1 1596/4885
US-11819559-B2 Cosmetic compositions comprising an antimicrobial system with reduced eye irritation or discomfort GK, PIR, LAGE3 TRPA1 132/4885CYP1A2 1464/4885EPHX1 1596/4885
US-20030066141-A1 Hair dye compositions HAAO, SRD5A1, GLA TRPA1 839/4885CYP1A2 552/4885EPHX1 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.