SCHEMBL12232086

SCHEMBL12232086

c1ccc(-n2c(-c3cc(-c4cc(-c5cccnc5)cc(-c5nnc(-c6cccnc6)o5)c4)ccc3-c3cccnc3)nc3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 1/20 0.43
▸ NPC1 O15118 7/20 0.41
▸ RAB9A P51151 6/20 0.41
▸ GUSB P08236 1/20 0.41
▸ ESR1 P03372 1/20 0.40
▸ ESR2 Q92731 1/20 0.40
▸ TP53 P04637 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ AOC3 Q16853 1/20 0.39
▸ MAPK1 P28482 2/20 0.38
▸ KDM4E B2RXH2 2/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ CYP11B2 P19099 1/20 0.38
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12232068 0.91 RECQL (0.47) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232080 0.89 AOC3 (0.46) RECQLNPC1RAB9AGUSBESR1
SCHEMBL12232109 0.89 AOC3 (0.45) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232114 0.89 ESR1 (0.49) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232081 0.87 MAPT (0.44) NPC1RAB9AGUSBESR1ESR2
SCHEMBL12232087 0.85 ESR1 (0.49) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232083 0.82 MAPT (0.41) RECQLNPC1RAB9AGUSBESR1
SCHEMBL12232067 0.79 ESR1 (0.52) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232069 0.79 ESR1 (0.55) RECQLESR1ESR2MAPTAOC3
SCHEMBL12232104 0.79 ESR1 (0.55) RECQLESR1ESR2MAPTAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772632-B2 Compound for organic photoelectric device, organic photoelectric device including the same, and display device including the same CHEIL INDUSTRIES, INC. (KR) 2014-07-08 — — US disclosed
US-8772632-B2 Compound for organic photoelectric device, organic photoelectric device including the same, and display device including the same CHEIL INDUSTRIES, INC. (KR) 2014-07-08 — — US disclosed
US-20130274471-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME IN KYU-YEON (KR) 2013-10-17 — — US disclosed
US-20130274471-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME IN KYU-YEON (KR) 2013-10-17 — — US disclosed
US-8383932-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2013-02-26 — — US disclosed
US-8383932-B2 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2013-02-26 — — US disclosed
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 — — US disclosed
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME CHEIL INDUSTRIES, INC. (KR) 2011-10-27 — — US disclosed
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-08-12 — — US disclosed
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same CHEIL INDUSTRIES, INC. (KR) 2010-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110260153-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING THE SAME PPOX, AOX1, OR10J3 RECQL 1511/4885NPC1 4362/4885RAB9A 2851/4885
US-20100200054-A1 Compound for organic photoelectric device and organic photoelectric device including the same PPOX, PIEZO1, AOX1 RECQL 1323/4885NPC1 3837/4885RAB9A 2341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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