SCHEMBL1223271

SCHEMBL1223271

CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)O)cc3)[nH]c2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 20/20 1.00
ADORA2A P29274 7/20 1.00
KDM4E B2RXH2 2/20 1.00
MEN1 O00255 2/20 1.00
ALDH1A1 P00352 2/20 1.00
GLA P06280 2/20 1.00
HPGD P15428 2/20 1.00
TSHR P16473 2/20 1.00
KMT2A Q03164 2/20 1.00
HSD17B10 Q99714 2/20 1.00
CYP2D6 P10635 1/20 1.00
ALOX15 P16050 1/20 1.00
CYP2C19 P33261 1/20 1.00
ADORA3 P0DMS8 4/20 0.77
ADORA1 P30542 3/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494961 0.83 ADORA2B (1.00) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL1321892 0.83 ADORA2B (1.00) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL10806711 0.82 ADORA2B (0.98) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL14129146 0.80 ADORA2B (0.94) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL17387706 0.80 ADORA2B (1.00) ADORA2BADORA2AADORA3ADORA1
SCHEMBL16099412 0.79 ADORA2B (1.00) ADORA2BADORA2AADORA3ADORA1
SCHEMBL25090489 0.78 ADORA2B (0.73) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL2686167 0.77 ADORA2B (0.68) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL1223393 0.76 ADORA2B (1.00) ADORA2BADORA2AKDM4EMEN1ALDH1A1
SCHEMBL31060455 0.76 ADORA2B (1.00) ADORA2BADORA2AADORA3ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024216134-A1 COMBINATORIAL STRATEGIES TO ENHANCE VACCINIA VIRUS IN VITRO AND IN VIVO ONCOLYSIS UNIVERSITY OF MIAMI (US) 2024-10-17 WO claimed
US-20240219394-A1 METHOD FOR MEASURING RESPONSE OF OLFACTORY RECEPTOR TO SUBSTANCE AJINOMOTO CO., INC. (JP) 2024-07-04 US claimed
EP-4382612-A1 METHOD FOR MEASURING RESPONSE OF OLFACTORY RECEPTOR TO SUBSTANCE AJINOMOTO CO., INC. (JP) 2024-06-12 EP claimed
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION 2023-09-14 US claimed
WO-2023039578-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER OMEROS CORPORATION (US) 2023-03-16 WO claimed
WO-2023013791-A1 METHOD FOR MEASURING RESPONSE OF OLFACTORY RECEPTOR TO SUBSTANCE 味の素株式会社 2023-02-09 WO claimed
US-20150297623-A1 METHODS FOR TREATMENT OF PRIMARY CANCER AND CANCER METASTASIS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2015-10-22 US claimed
US-20260124299-A1 BITE-ACTIVATED CAR-T CELLS Vivia Biotech Sl (ES) 2026-05-07 US disclosed
US-20260125449-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY JUNO THERAPEUTICS, INC. (US) 2026-05-07 US disclosed
US-20260109774-A1 CHIMERIC ANTIGEN RECEPTORS SPECIFIC FOR B-CELL MATURATION ANTIGEN AND ENCODING POLYNUCLEOTIDES JUNO THERAPEUTICS, INC. (US) 2026-04-23 US disclosed
US-12583904-B2 Articles of manufacture and methods for treatment using adoptive cell therapy JUNO THERAPEUTICS, INC. (US) 2026-03-24 US disclosed
US-20260070892-A1 FUNCTIONALIZED AMINOTRIAZINES LEADXPRO AG (CH) 2026-03-12 US disclosed
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof HALOZYME HYPERCON, INC. (US) 2026-03-10 US disclosed
EP-2118100-A1 NEW 3- ([1,2,4] TRIAZOLO [4,3-A] PYRIDIN-7-YL)BENZAMIDE DERIVATIVES Almirall, S.A. (ES) 2009-11-18 EP disclosed
WO-2009132774-A1 NEW SUBSTITUTED INDOLIN-2-ONE DERIVATIVES AND THEIR USE AS P39 MITOGEN-ACTIVATED KINASE INHIBITORS ALMIRALL, S. A. (ES) 2009-11-05 WO disclosed
EP-2113503-A1 New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors Laboratorios Almirall, S.A. (ES) 2009-11-04 EP disclosed
WO-2009124692-A1 NEW SUBSTITUTED SPIRO[CYCLOALKYL-1,3'-INDOL]-2'(1'H)-ONE DERIVATIVES AND THEIR USE AS P38 MITOGEN-ACTIVATED KINASE INHIBITORS. ALMIRALL, S.A. (ES) 2009-10-15 WO disclosed
EP-2108641-A1 New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors Laboratorios Almirall, S.A. (ES) 2009-10-14 EP disclosed
WO-2008131922-A1 NEW 4,8-DIPHENYL-POLYAZANAPHTHALENE DERIVATIVES ALMIRALL, S.A. (ES) 2008-11-06 WO disclosed
WO-2008107125-A1 NEW 3-([1,2,4]TRIAZOLO[4,3-A]PYRIDIN-7-YL)BENZAMIDE DERIVATIVES ALMIRALL, S.A. (ES) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof ALB, S100P, S100A8 ADORA2B 3145/4885ADORA2A 2833/4885KDM4E 3147/4885
US-20260109774-A1 CHIMERIC ANTIGEN RECEPTORS SPECIFIC FOR B-CELL MATURATION ANTIGEN AND ENCODING POLYNUCLEOTIDES CD2BP2, CD22, FCGR2A ADORA2B 2764/4885ADORA2A 2778/4885KDM4E 2334/4885
US-20260070892-A1 FUNCTIONALIZED AMINOTRIAZINES ADORA2B, TBXA2R, CNR1 ADORA2B 1/4885ADORA2A 7/4885KDM4E 1854/4885
US-20230285556-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER TP53, CD4, MCL1 ADORA2B 2902/4885ADORA2A 1801/4885KDM4E 2914/4885
US-12583904-B2 Articles of manufacture and methods for treatment using adoptive cell therapy CD4, CD2, ICOS ADORA2B 3663/4885ADORA2A 1019/4885KDM4E 2844/4885
US-20260125449-A1 ARTICLES OF MANUFACTURE AND METHODS FOR TREATMENT USING ADOPTIVE CELL THERAPY MALT1, BCL9, ICOS ADORA2B 3782/4885ADORA2A 2189/4885KDM4E 658/4885
US-20150297623-A1 METHODS FOR TREATMENT OF PRIMARY CANCER AND CANCER METASTASIS P2RY1, P2RX3, P2RY4 ADORA2B 16/4885ADORA2A 8/4885KDM4E 2872/4885
US-20260124299-A1 BITE-ACTIVATED CAR-T CELLS TNFRSF9, ICOS, CD2 ADORA2B 1982/4885ADORA2A 2086/4885KDM4E 1387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.