Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12232282 | 0.88 | MMP2 (0.42) | — | |
| SCHEMBL12232703 | 0.86 | CHRM2 (0.45) | CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL12232520 | 0.86 | CHRM2 (0.48) | CHRM2CHRM1CHRM5CHRM3CHRM4 | |
| SCHEMBL12232500 | 0.86 | ADAMTS5 (0.44) | — | |
| SCHEMBL12508554 | 0.85 | GRIN2D (0.49) | — | |
| SCHEMBL12232515 | 0.85 | CHRM2 (0.44) | CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL12233005 | 0.80 | MAPT (0.54) | — | |
| SCHEMBL12232286 | 0.79 | CHRNA7 (0.42) | — | |
| SCHEMBL12232681 | 0.79 | MMP2 (0.42) | — | |
| SCHEMBL12232802 | 0.78 | MAPT (0.42) | CHRM2CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251212-A1 | PIPERAZINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251212-A1 | PIPERAZINE DERIVATIVES | GRIN2C, NR2C2, GRIN3A | CHRM2 108/4885CHRM1 75/4885CHRM5 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.