Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12234191 | 0.80 | HDAC3 (0.35) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL14822741 | 0.78 | LPAR3 (0.39) | LPAR3LPAR2LPAR1HDAC3HDAC1 | |
| SCHEMBL12257897 | 0.77 | MVD (0.47) | MVDLPAR3LPAR2LPAR1CYP1A2 | |
| SCHEMBL12234263 | 0.76 | TSHR (0.34) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL23768567 | 0.76 | CYP2C9 (0.40) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL882496 | 0.76 | TDP1 (0.39) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL4202803 | 0.75 | TSHR (0.43) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL12234244 | 0.75 | MVD (0.45) | MVDLPAR3LPAR2LPAR1HDAC2 | |
| SCHEMBL22145756 | 0.74 | HDAC3 (0.36) | CYP1A2CYP2C9CYP2C19HTTHDAC3 | |
| SCHEMBL12234242 | 0.73 | CYP1A2 (0.31) | CYP1A2CYP2C9CYP2C19HTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2011-10-27 | — | — | US | disclosed |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2010-12-23 | — | — | US | disclosed |
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | JEAN FRANCOIS | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168225-A1 | Small-Molecule Hepatitis C Virus (HCV) NS3/4A Serine Protease Inhibitors | SRR, HAVCR2, CBR3 | MVD 4583/4885LPAR3 472/4885LPAR2 1899/4885 |
| US-20100323990-A1 | SHIP 1 MODULATOR PRODRUGS | PPM1D, PPM1G, PPM1F | MVD 537/4885LPAR3 1362/4885LPAR2 985/4885 |
| US-20110263539-A1 | SHIP 1 MODULATOR COMPOUNDS | PPM1F, PPM1D, PPP1R1B | MVD 1074/4885LPAR3 1474/4885LPAR2 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.