Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882496 | 0.82 | TDP1 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL23768567 | 0.82 | CYP2C9 (0.40) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12234191 | 0.78 | HDAC3 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20087381 | 0.78 | TDP1 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4202803 | 0.77 | TSHR (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL26337010 | 0.77 | CES1 (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13062086 | 0.77 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9784216 | 0.77 | CYP1A2 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1845681 | 0.75 | HTT (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12234263 | 0.74 | TSHR (0.34) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210285955-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | WARP DRIVE BIO, INC. | 2021-09-16 | — | — | US | disclosed |
| US-20200199102-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | Revolution Medicines, Inc. | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210285955-A1 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | FKBP8, PIN1, FKBP1A | HDAC3 3255/4885HDAC1 1846/4885HDAC2 2454/4885 |
| US-20200199102-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | PIN1, FKBP14, FKBP2 | HDAC3 1907/4885HDAC1 658/4885HDAC2 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.