Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.63 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223203 | 0.86 | PGR (0.66) | PGRNR3C2AR | |
| SCHEMBL3874025 | 0.83 | PGR (0.65) | PGR | |
| SCHEMBL4816287 | 0.83 | PGR (0.65) | PGRNR3C2AR | |
| SCHEMBL3985058 | 0.83 | PGR (0.67) | PGRNR3C2AR | |
| SCHEMBL4909392 | 0.82 | PGR (0.48) | PGRNR3C2AR | |
| SCHEMBL27544026 | 0.80 | PGR (0.64) | PGRNR3C2ARPDE3BPDE3A | |
| SCHEMBL11903478 | 0.80 | PGR (0.53) | PGR | |
| SCHEMBL3982376 | 0.79 | PGR (0.57) | PGRNR3C2AR | |
| SCHEMBL3989246 | 0.78 | PGR (0.69) | PGRNR3C2AR | |
| SCHEMBL4809621 | 0.78 | PGR (1.00) | PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476262-B2 | Cyanopyrroles | WYETH LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110039839-A1 | Cyanopyrroles | WYETH LLC (US) | 2011-02-17 | — | — | US | disclosed |
| EP-1173433-B1 | CYANOPYRROLES AS PROGESTERONE RECEPTOR AGONISTS | WYETH CORP (US) | 2005-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039839-A1 | Cyanopyrroles | PGR, MC2R, THRB | PGR 1/4885NR3C2 4/4885AR 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.