SCHEMBL12236900

SCHEMBL12236900

CO[C@@H]1CO[C@@H](OC2C(NC(C)=O)[C@H](C)OC(CO)[C@H]2O)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CD69 Q07108 1/20 0.44
▸ LGALS3 P17931 6/20 0.42
▸ LGALS8 O00214 3/20 0.42
▸ LGALS4 P56470 1/20 0.42
▸ MAPK1 P28482 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40
▸ LGALS1 P09382 1/20 0.39
▸ LGALS7; LGALS7B P47929 1/20 0.39
▸ LGALS9 O00182 1/20 0.38
▸ PYGB P11216 1/20 0.36
▸ CHIA Q9BZP6 1/20 0.36
▸ SELL P14151 1/20 0.36
▸ SELP P16109 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14925198 1.00 CD69 (0.44) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL17131368 1.00 CD69 (0.44) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL18022304 0.90 CD69 (0.47) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL23491004 0.89 CD69 (0.49) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL13895616 0.89 CD69 (0.49) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL2602688 0.83 LGALS3 (0.49) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL14091725 0.82 LGALS3 (0.47) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL18589695 0.82 LGALS3 (0.47) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL16745289 0.82 MAPK1 (0.41) CD69LGALS3LGALS8LGALS4MAPK1
SCHEMBL12694356 0.81 LGALS3 (0.58) CD69LGALS3LGALS8LGALS4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8039447-B2 Derivatives of hyaluronic acid, their preparation process and their uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2011-10-18 — — US disclosed
US-20080306023-A1 Derivatives of Hyaluronic Acid, Their Preparation Process and Their Uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2008-12-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306023-A1 Derivatives of Hyaluronic Acid, Their Preparation Process and Their Uses CD44, F12, F11 CD69 1600/4885LGALS3 553/4885LGALS8 813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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