Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.54 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921762 | 0.87 | DPP4 (0.64) | DPP4CARM1PRMT6ST14MAOB | |
| SCHEMBL32670327 | 0.86 | CARM1 (0.51) | DPP4CARM1PRMT6ALDH1A1RHEB | |
| Hydrochloric Acid SCHEMBL2787535 | 0.86 | DPP4 (0.62) | DPP4CARM1PRMT6ST14MAOB | |
| SCHEMBL12239021 | 0.83 | ALDH1A1 (0.48) | DPP4CARM1PRMT6ST14MAOB | |
| SCHEMBL6826223 | 0.81 | MAOA (0.50) | DPP4CARM1PRMT6MAOBALDH1A1 | |
| SCHEMBL31448129 | 0.81 | MAOA (0.50) | DPP4CARM1PRMT6MAOBALDH1A1 | |
| SCHEMBL3667279 | 0.79 | DPP4 (0.61) | DPP4CARM1PRMT6ALDH1A1RHEB | |
| SCHEMBL11402635 | 0.78 | MEN1 (0.48) | DPP4CARM1PRMT6ALDH1A1RHEB | |
| SCHEMBL31447979 | 0.77 | CARM1 (0.47) | DPP4CARM1PRMT6ALDH1A1RHEB | |
| SCHEMBL8115750 | 0.76 | DPP4 (0.50) | DPP4CARM1PRMT6ALDH1A1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-8916589-B2 | Bradykinin B1-antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-27 | — | — | US | disclosed |
| WO-2009027450-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263626-A1 | NOVEL BRADYKININ B1-ANTAGONISTS | BDKRB1, BDKRB2, EDNRB | DPP4 3173/4885CARM1 3858/4885PRMT6 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.