Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 2/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239156 | 0.86 | PRKAA2 (0.59) | PRKAA2ADRB2HRH3CHRM4 | |
| SCHEMBL1006219 | 0.86 | PRKAA2 (0.62) | PRKAA2ADRB2HRH3KDM4EALDH1A1 | |
| SCHEMBL19892721 | 0.85 | KDM4E (0.57) | PRKAA2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL425198 | 0.79 | HRH3 (0.56) | PRKAA2HRH3KDM4ELMNAABL1 | |
| SCHEMBL519004 | 0.78 | PRKAA2 (1.00) | PRKAA2ADRB2 | |
| SCHEMBL13279374 | 0.77 | PRKAA2 (0.55) | PRKAA2HRH3KDM4EALDH1A1LMNA | |
| SCHEMBL385239 | 0.77 | KDM4E (0.48) | PRKAA2HRH3KDM4ELMNAABL1 | |
| SCHEMBL16433602 | 0.76 | SCD (0.48) | PRKAA2HRH3KDM4ELMNASMN1; SMN2 | |
| SCHEMBL16433609 | 0.75 | HRH3 (0.55) | HRH3KDM4ELMNAABL1 | |
| SCHEMBL11956890 | 0.75 | KDM4E (0.51) | HRH3KDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | PRKAA2 2325/4885ADRB2 131/4885HRH3 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.