SCHEMBL425198

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16433609	0.93	HRH3 (0.55)	HRH3ACACBKDM4EABL1LMNA
	SCHEMBL19892721	0.92	KDM4E (0.57)	HRH3ACACBKDM4EABL1LMNA
	SCHEMBL13279374	0.82	PRKAA2 (0.55)	HRH3ACACBKDM4EABL1LMNA
	SCHEMBL23708918	0.81	HRH3 (0.53)	HRH3KDM4EABL1LMNALIPG
	SCHEMBL23636802	0.80	LIPG (0.48)	ACACBLIPGLPLLIPC
	SCHEMBL6573621	0.79	HRH3 (0.59)	HRH3ACACBKDM4EABL1LMNA
	SCHEMBL7958655	0.79	LIPG (0.50)	ACACBCYP3A4LIPGLPLLIPC
	SCHEMBL23702831	0.79	PDE10A (0.49)	HRH3KDM4EABL1LMNALIPG
	SCHEMBL23702830	0.79	PDE10A (0.49)	HRH3KDM4EABL1LMNALIPG
	SCHEMBL12239157	0.79	PRKAA2 (0.64)	HRH3KDM4EABL1LMNAPRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.