Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD2 | P25440 | 2/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239338 | 0.87 | KIF11 (0.34) | WNT3ATNKS2BRD4BRD2BRD3 | |
| SCHEMBL12239267 | 0.86 | HDAC1 (0.35) | — | |
| SCHEMBL12239269 | 0.84 | HDAC1 (0.35) | BRD4BAZ2A | |
| SCHEMBL12239274 | 0.84 | HDAC3 (0.32) | BRD4BAZ2A | |
| SCHEMBL16975835 | 0.80 | GSK3A (0.31) | BRD4BRD2BRD3MAPT | |
| SCHEMBL12239273 | 0.80 | BACE1 (0.33) | GRM2JAK2 | |
| SCHEMBL12239201 | 0.79 | OPRL1 (0.34) | — | |
| SCHEMBL1652187 | 0.79 | OPRL1 (0.34) | — | |
| SCHEMBL2040835 | 0.79 | — | — | |
| SCHEMBL1653411 | 0.78 | BRD4 (0.31) | BRD4BAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313370-B1 | 5-HETEROCYCLYLALKYL-3-HYDROXY-2-PHENYLCYCLOPENT-2-ENONES AS HERBICIDES | SYNGENTA LTD (GB) | 2015-08-19 | — | — | EP | disclosed |
| US-9096560-B2 | 5-heterocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enones as herbicides | SYNGENTA LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| US-9096560-B2 | 5-heterocyclylalkyl-3-hydroxy-2-phenylcyclopent-2-enones as herbicides | SYNGENTA LIMITED (GB) | 2015-08-04 | — | — | US | disclosed |
| US-20130053385-A1 | METHOD OF COMBATING AND CONTROLLING PESTS | SYNGENTA LIMITED (GB) | 2013-02-28 | — | — | US | disclosed |
| US-20130053385-A1 | METHOD OF COMBATING AND CONTROLLING PESTS | SYNGENTA LIMITED (GB) | 2013-02-28 | — | — | US | disclosed |
| US-20110263428-A1 | 5-HETEROCYCLYLALKYL-3-HYDROXY-2-PHENYLCYCLOPENT-2-ENONES AS HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2011073060-A2 | METHOD OF COMBATING AND CONTROLLING PESTS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-23 | — | — | WO | disclosed |
| WO-2010000773-A1 | 5-HETEROCYCLYLALKYL-3-HYDROXY-2-PHENYLCYCLOPENT-2-ENONES AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263428-A1 | 5-HETEROCYCLYLALKYL-3-HYDROXY-2-PHENYLCYCLOPENT-2-ENONES AS HERBICIDES | DDT, CYP1B1, AHR | PRKDC 2904/4885WNT3A 3205/4885TNKS2 3791/4885 |
| US-20130053385-A1 | METHOD OF COMBATING AND CONTROLLING PESTS | ACHE, ALG1, KEAP1 | PRKDC 4481/4885WNT3A 2802/4885TNKS2 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.