SCHEMBL12242501

SCHEMBL12242501

C=CC(=O)Cc1ccc(C#Cc2c(F)cc(-c3ccc(COC(=O)C=C)cc3)cc2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.33
FFAR1 O14842 1/20 0.32
ACACB O00763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12242554 1.00 ENPP2 (0.33) ENPP2FFAR1ACACB
SCHEMBL12242502 0.89 FFAR1 (0.39) ENPP2FFAR1ACACB
SCHEMBL12242527 0.85 FFAR1 (0.41) FFAR1ACACB
SCHEMBL12242484 0.85 FFAR1 (0.41) FFAR1ACACB
SCHEMBL12242486 0.80 FFAR1 (0.41) FFAR1ACACB
SCHEMBL12242489 0.80 ASIC3 (0.38) FFAR1ACACB
SCHEMBL12242553 0.79 FFAR1 (0.35) FFAR1
SCHEMBL12242496 0.78 MET (0.37) FFAR1ACACB
SCHEMBL12242495 0.78 FFAR1 (0.34) FFAR1ACACB
SCHEMBL12242557 0.76 FFAR1 (0.35) ENPP2FFAR1ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8460576-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-06-11 US disclosed
US-20110253936-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-10-20 US disclosed