SCHEMBL12242515

SCHEMBL12242515

C=CC(=O)COc1ccc(C#Cc2ccc(C(=O)Oc3ccc(OCOC(=O)C=C)c(F)c3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.32
THRB P10828 1/20 0.31
ACACB O00763 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12242538 0.90 CASP3 (0.35)
SCHEMBL12242482 0.89 FFAR1 (0.37) FFAR1THRBACACB
SCHEMBL12242514 0.88 ACHE (0.38)
SCHEMBL12242511 0.87 FFAR1 (0.38) FFAR1THRBACACB
SCHEMBL12242536 0.86 KDM4E (0.33) THRB
SCHEMBL12242534 0.84 FFAR1 (0.37) FFAR1THRBACACB
SCHEMBL12733822 0.83 THRB (0.37) THRB
SCHEMBL12154265 0.83 MAPT (0.34) FFAR1THRB
SCHEMBL12733716 0.81 THRB (0.39) THRB
SCHEMBL12242566 0.81 FFAR1 (0.39) FFAR1THRBACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8460576-B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same DIC CORPORATION (JP) 2013-06-11 US disclosed
US-20110253936-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2011-10-20 US disclosed