Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.34 |
| ▸ | ADH1C | P00326 | 3/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.34 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247501 | 1.00 | ADH1B (0.34) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL12247688 | 1.00 | ADH1B (0.34) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL28148086 | 0.77 | KCNK3 (0.39) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL18696198 | 0.74 | ALDH1A1 (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL27914154 | 0.74 | ALDH1A1 (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL28441659 | 0.74 | ALDH1A1 (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL27551180 | 0.71 | HTT (0.38) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL28138761 | 0.70 | ADH1B (0.43) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL27879636 | 0.69 | CHRM2 (0.37) | ADH1BADH1CADH1AADH7CHRM2 | |
| SCHEMBL6967770 | 0.68 | POLB (0.36) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044206-B2 | Nitrogen—containing heterocyclic derivatives having 2,6-disubstituted styryl | ASTELLAS PHARMA INC. (JP) | 2011-10-25 | — | — | US | disclosed |