SCHEMBL12248133

SCHEMBL12248133

Cc1cnc2cc(/C=C/c3ccc4c(ccc5cc(/C=C/c6ccc7nc(C)cnc7c6)ccc54)c3)ccc2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGFBR1 P36897 1/20 0.40
▸ PAX8 Q06710 1/20 0.36
▸ PDGFRB P09619 3/20 0.36
▸ PDGFRA P16234 3/20 0.36
▸ MAPT P10636 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ CASP3 P42574 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36
▸ IP6K1 Q92551 2/20 0.35
▸ EGFR P00533 1/20 0.35
▸ SRC P12931 2/20 0.33
▸ RELA Q04206 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ APOBEC3A P31941 1/20 0.33
▸ APOBEC3G Q9HC16 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12248134 0.81 CYP1A2 (0.53) MAPTMEN1NPC1CASP3RAB9A
SCHEMBL12248132 0.81 CYP1A2 (0.47) TGFBR1PAX8PDGFRBPDGFRAMAPT
SCHEMBL28596237 0.78 KDM4E (0.38) TGFBR1MAPTMEN1NPC1RAB9A
SCHEMBL13410163 0.73 CYP1A2 (0.61) MAPTMEN1NPC1CASP3RAB9A
SCHEMBL13784723 0.72 CYP1A2 (0.39) PDGFRBPDGFRANPC1RAB9AEGFR
SCHEMBL14829741 0.71 TGFBR1 (0.42) TGFBR1MAPTMEN1NPC1RAB9A
SCHEMBL4586485 0.71 TGFBR1 (0.39) TGFBR1PAX8PDGFRBNPC1RAB9A
SCHEMBL6844954 0.71 CYP1A2 (0.54) MAPTNPC1RAB9AEGFRCYP1A2
SCHEMBL29639043 0.71 CYP1A2 (0.54) MAPTNPC1RAB9AEGFRCYP1A2
SCHEMBL18674406 0.69 S100A4 (0.43) MAPTRELACYP1A2APOBEC3AAPOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2083456-B1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR IDEMITSU KOSAN CO (JP) 2013-01-02 — — EP disclosed
US-8022401-B2 Organic thin film transistor and organic thin film light-emitting transistor IDEMITSU KOSAN, CO., LTD. (JP) 2011-09-20 — — US disclosed
US-8022401-B2 Organic thin film transistor and organic thin film light-emitting transistor IDEMITSU KOSAN, CO., LTD. (JP) 2011-09-20 — — US disclosed
US-20090256145-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR DEMITSU KOSAN 3-CHOME, CHIYODA-KU (JP) 2009-10-15 — — US disclosed
US-20090256145-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR DEMITSU KOSAN 3-CHOME, CHIYODA-KU (JP) 2009-10-15 — — US disclosed
EP-2083456-A1 ORGANIC THIN FILM TRANSISTOR AND ORGANIC THIN FILM LIGHT-EMITTING TRANSISTOR Idemitsu Kosan Co., Ltd. (JP) 2009-07-29 — — EP disclosed
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