Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564352 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL15474206 | 0.85 | SMN1; SMN2 (0.42) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL12255163 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL12255338 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL9880894 | 0.80 | ACACA (0.44) | ALDH1A1LMNASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL12255174 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL12028455 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL17490664 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL15367929 | 0.77 | ALDH1A1 (0.35) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E | |
| SCHEMBL19792672 | 0.76 | TSHR (0.42) | ALDH1A1LMNASMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012964-B2 | 9-substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20070190071-A1 | 9-Substituted 8-oxoadenine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190071-A1 | 9-Substituted 8-oxoadenine compound | IFNAR1, IL5, IFNG | ALDH1A1 3672/4885LMNA 4406/4885SMN1; SMN2 2719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.