SCHEMBL1225568

SCHEMBL1225568

CC=CCCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC1 Q13547 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225567 1.00 SIGMAR1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5852908 0.94 TRPV1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5852915 0.94 TRPV1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5855428 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL10597706 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5853429 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5854277 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5854280 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5853432 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5855432 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119314723-A Crosslinked polyethylene insulating material, and preparation method and application thereof 北京怀柔实验室 2025-01-14 CN claimed
CN-102274701-B Surfactant, preparation and application thereof PETROCHINA CO LTD 2014-04-02 CN claimed
CN-102274701-A Surfactant, preparation and application thereof 2011-12-14 CN claimed
US-20110207637-A1 Vicinally Disubstituted Internal Olefins as Constituents of Olefin Copolymers for Lubricating Oil Rheology Modifiers EXXONMOBIL CHEMICAL PATENTS INC. 2011-08-25 US claimed
EP-2280075-A1 Biocatalyst for catalytic hydroamination BASF SE (DE) 2011-02-02 EP claimed
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US claimed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO claimed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US claimed
CN-119314723-A Crosslinked polyethylene insulating material, and preparation method and application thereof 北京怀柔实验室 2025-01-14 CN disclosed
CN-112920123-B 3-aryl-6-aralkyl-1, 4,5, 6-tetrahydropyrazines compound and preparation method and application thereof 江苏冠瑜生物科技有限公司 2022-09-16 CN disclosed
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-04-19 US disclosed
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2021-06-03 US disclosed
CN-108699246-A Durable superhydrophobic coatings 新加坡科技研究局 2018-10-23 CN disclosed
EP-3386936-A1 OLEFIN METATHESIS CATALYSTS Umicore AG & Co. KG (DE) 2018-10-17 EP disclosed
WO-2000048750-A1 POLYMER-COATED METAL COMPOSITES BY DIP AUTOPOLYMERIZATION UNIVERSITY OF CONNECTICUT (US) 2000-08-24 WO disclosed
WO-1998043649-A2 AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-10-08 WO disclosed
CN-1130377-A Cyclic amide derivatives OTSUKA PHARMA CO LTD (JP) 1996-09-04 CN disclosed
US-5422360-A Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-06-06 US disclosed
US-5418256-A Hydrocarbon solvent, degrading and extracting, hydrocarbon reaction products UNIVERSITY OF SOUTH ALABAMA (US) 1995-05-23 US disclosed
EP-0531812-A1 Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210163377-A1 CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS MSMO1, CYP2E1, PNMT SIGMAR1 1368/4885MEN1 97/4885KMT2A 473/4885
US-11306041-B2 Catalytic synthesis of super linear alkenyl arenes using rhodium catalysts MSMO1, CYP2E1, PNMT SIGMAR1 1368/4885MEN1 97/4885KMT2A 473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.