SCHEMBL1225567

SCHEMBL1225567

C/C=C/CCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC1 Q13547 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1225568 1.00 SIGMAR1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5852908 0.94 TRPV1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5852915 0.94 TRPV1 (0.50) SIGMAR1MEN1KMT2AHDAC3MAPK1
SCHEMBL5855428 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL10597706 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5853429 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5854277 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5854280 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5853432 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA
SCHEMBL5855432 0.92 TRPV1 (0.53) SIGMAR1MEN1KMT2AL3MBTL1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119314723-A Crosslinked polyethylene insulating material, and preparation method and application thereof 北京怀柔实验室 2025-01-14 CN claimed
EP-2280075-A1 Biocatalyst for catalytic hydroamination BASF SE (DE) 2011-02-02 EP claimed
CN-119314723-A Crosslinked polyethylene insulating material, and preparation method and application thereof 北京怀柔实验室 2025-01-14 CN disclosed
WO-2017111702-A9 DURABLE SUPERHYDROPHOBIC COATING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-07-19 WO disclosed
WO-2017111702-A1 DURABLE SUPERHYDROPHOBIC COATING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-29 WO disclosed
US-9636670-B2 Catalysts, ligands and use thereof OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2017-05-02 US disclosed
US-20160074852-A1 CATALYSTS, LIGANDS AND USE THEREOF ISIS INNOVATION LIMITED (GB) 2016-03-17 US disclosed
EP-2986375-A2 CATALYSTS, LIGANDS AND USE THEREOF Isis Innovation Limited (GB) 2016-02-24 EP disclosed
WO-2014170642-A2 CATALYSTS, LIGANDS AND USE THEREOF ISIS INNOVATION LIMITED (GB) 2014-10-23 WO disclosed
EP-2459727-A2 BIOCATALYST FOR CATALYTIC HYDROAMINATION BASF SE (DE) 2012-06-06 EP disclosed
US-20120123155-A1 BIOCATALYST FOR CATALYTIC HYDROAMINATION BASF SE (DE) 2012-05-17 US disclosed
CN-101068810-B Carbostyril compound OTSUKA PHARMA CO LTD 2011-02-09 CN disclosed
WO-2011012632-A2 BIOCATALYST FOR CATALYTIC HYDROAMINATION BASF SE (DE) 2011-02-03 WO disclosed
EP-2280075-A1 Biocatalyst for catalytic hydroamination BASF SE (DE) 2011-02-02 EP disclosed
CN-101068810-A Carbostyril compound OTSUKA PHARMA CO LTD (JP) 2007-11-07 CN disclosed
US-7037989-B2 Copolymers of ethylene and/or α-olefins and vicinally disubstituted olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-02 US disclosed
WO-2004106394-A1 COPOLYMERS OF ETHYLENE AND/OR α-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO disclosed
US-20040242814-A1 COPOLYMERS OF ETHYLENE AND/OR ALPHA-OLEFINS AND VICINALLY DISUBSTITUTED OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-02 US disclosed
CN-1084330-C Cydic amide derivatives OTSUKA PHARMA CO LTD (JP) 2002-05-08 CN disclosed
CN-1130377-A Cyclic amide derivatives OTSUKA PHARMA CO LTD (JP) 1996-09-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120123155-A1 BIOCATALYST FOR CATALYTIC HYDROAMINATION HDHD5, PAH, GRHPR SIGMAR1 3090/4885MEN1 3127/4885KMT2A 2124/4885
US-20160074852-A1 CATALYSTS, LIGANDS AND USE THEREOF SPR, SQOR, COASY SIGMAR1 367/4885MEN1 3986/4885KMT2A 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.