SCHEMBL122563

SCHEMBL122563

CC(C)(C)c1ccc(C(=O)OO)c(C(C)(C)C)c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GLRA3 O75311 1/20 0.40
GLRB P48167 1/20 0.40
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
ATM Q13315 1/20 0.32
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
NR1H4 Q96RI1 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 2/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122561 0.90 POLB (0.38) GLRA3GLRBCA12CA1CA2
SCHEMBL122560 0.87 GLRA3 (0.40) GLRA3GLRBRXRARXRBRXRG
SCHEMBL1716755 0.87 GLRA3 (0.40) GLRA3GLRBCA12CA1CA2
SCHEMBL4939017 0.84 GLRA3 (0.46) GLRA3GLRBCA12CA1CA2
Water SCHEMBL8079256 0.83 GLRA3 (0.44) GLRA3GLRBRXRBTDP1NR1H4
SCHEMBL1679222 0.82 MAPT (0.41) CA2RXRARXRBRXRGTDP1
SCHEMBL11216809 0.81 TDP1 (0.40) RXRBTDP1POLBMAPTNR1H4
SCHEMBL1348416 0.81 KMT2A (0.33) TDP1POLBMAPT
SCHEMBL382358 0.81 GLRA3 (0.36) GLRA3GLRBRXRARXRBRXRG
SCHEMBL11177188 0.80 MAPT (0.34) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-4011619-B1 RESIN COMPOSITION FOR METAL-CLAD LAMINATES, PREPREG, AND METAL-CLAD LAMINATE NIPPON SODA CO (JP) 2024-12-04 EP claimed
CN-111372372-B Circuit material and circuit board comprising same 广东生益科技股份有限公司 2023-12-22 CN claimed
CN-111253702-B Resin composition, prepreg and circuit material using same 广东生益科技股份有限公司 2023-06-06 CN claimed
EP-3569591-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC Global Technologies B.V. (NL) 2019-11-20 EP claimed
US-20190337895-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-07 US claimed
US-10435368-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-08 US claimed
EP-3172188-B1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-09-04 EP claimed
US-20170166528-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2017-06-15 US claimed
EP-3172188-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC Global Technologies B.V. (NL) 2017-05-31 EP claimed
US-20010053820-A1 Poly(arylene ether)-containing thermoset composition, method for the preparation thereof, and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2001-12-20 US claimed
WO-2001053413-A1 CURABLE RESIN COMPOSITION, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2001-07-26 WO claimed
WO-2001040354-A1 POLY(PHENYLENE ETHER) - POLYVINYL THERMOSETTING RESIN GENERAL ELECTRIC COMPANY (US) 2001-06-07 WO claimed
EP-0687539-B1 Rubber composition for cleaning mold, and method for cleaning mold BRIDGESTONE CORP (JP) 1999-02-17 EP claimed
EP-0601572-B1 Method for producing a spherical ion exchange resin MITSUBISHI CHEM CORP (JP) 1997-10-15 EP claimed
EP-0546516-B1 Rubber composition for cleaning metal mold and method for cleaning BRIDGESTONE CORP (JP) 1996-09-25 EP claimed
EP-0506267-B1 Resin composition for making expanded thermoplastics patterns, patterns produced therefrom and their use in metal casting FOSECO INT (GB) 1996-06-26 EP claimed
US-4994703-A Piezoelectric element of laminate type MITSUBISHI KASEI CORPORATION (JP) 1991-02-19 US claimed
EP-0150952-B1 PHOTOPOLYMERIZABLE COMPOSITION KURARAY CO., LTD. (JP) 1989-08-30 EP claimed
EP-0106627-B1 METHOD FOR MANUFACTURE OF AQUEOUS SUSPENSION OF SOLID ORGANIC PEROXIDE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1985-09-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337895-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, HSPBP1 GLRA3 3423/4885GLRB 3736/4885CA12 2022/4885
US-20170166528-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF HSP90AA1, HSP90AB1, HSPBP1 GLRA3 3423/4885GLRB 3736/4885CA12 2022/4885
US-10435368-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, HSPBP1 GLRA3 3423/4885GLRB 3736/4885CA12 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.