Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177188 | 0.92 | MAPT (0.34) | TDP1CYP1A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4737878 | 0.89 | ALOX15 (0.43) | TDP1CYP1A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4942021 | 0.85 | CYP1A2 (0.50) | TDP1CYP1A2RXRBNR1H4EPHX2 | |
| SCHEMBL122560 | 0.81 | GLRA3 (0.40) | TDP1CYP1A2RXRBNR1H4EPHX2 | |
| SCHEMBL122563 | 0.81 | GLRA3 (0.40) | TDP1RXRBNR1H4ALDH1A1KDM4E | |
| SCHEMBL1348416 | 0.81 | KMT2A (0.33) | TDP1POLBMAPT | |
| Isophthalic Acid SCHEMBL31245588 | 0.81 | RXRA (0.43) | TDP1RXRBNR1H4KDM4ECYP2C9 | |
| SCHEMBL1348862 | 0.80 | MAPT (0.39) | TDP1ALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL1716755 | 0.78 | GLRA3 (0.40) | TDP1RXRBNR1H4ALDH1A1KDM4E | |
| SCHEMBL382358 | 0.78 | GLRA3 (0.36) | TDP1CYP1A2RXRBNR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009268-B1 | PROCESS FOR CROSS-LINKING SHAPED NON-POLAR SYNTHETIC RESINS AND ELECTRIC OBJECTS INSULATED WITH SAID CROSSLINKED RESINS | AKZO N.V. (NL) | 1982-12-01 | — | — | EP | claimed |