SCHEMBL12258609

SCHEMBL12258609

Cc1ccc(N(c2ccc(C=Cc3cccc4c(C#N)c(C#N)c5cccc(C)c5c34)cc2)c2cccc3ccccc23)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 2/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CHAT P28329 3/20 0.34
NFE2L2 Q16236 2/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
FGF23 Q9GZV9 1/20 0.32
HPGD P15428 2/20 0.32
APP P05067 1/20 0.32
ALOX12 P18054 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
S100A4 P26447 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10050171 0.93 ALDH1A1 (0.36) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL12309958 0.90 ALDH1A1 (0.36) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL12258606 0.84 NFE2L2 (0.40) ALDH1A1MAPTPKMALOX15MAPK1
SCHEMBL10050173 0.82 APP (0.43) ALDH1A1MAPTPKMALOX15MAPK1
SCHEMBL13930448 0.81 NFE2L2 (0.34) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL12258692 0.81 NFE2L2 (0.34) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL10075345 0.81 NFE2L2 (0.34) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL10050158 0.81 S100A4 (0.34) ALDH1A1MAPTPKMALOX15MAPK1
SCHEMBL10074380 0.81 ALDH1A1 (0.33) PTGS1PTGS2ALDH1A1MAPTPKM
SCHEMBL12309962 0.80 APP (0.41) PTGS1PTGS2ALDH1A1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8025986-B2 Light emitting region having a charge-transport, amine-containing steryl compound like 1-((2,5-dicyano)phenyl)ethylene-),4- ((p-methoxy-)phenyl)-amino(-(phenyl)benzene; heat resistance; accuracy; high purity and luminescence in long wavelength range (red); flat display panel; television SONY CORPORATION (JP) 2011-09-27 US disclosed
US-8025986-B2 Light emitting region having a charge-transport, amine-containing steryl compound like 1-((2,5-dicyano)phenyl)ethylene-),4- ((p-methoxy-)phenyl)-amino(-(phenyl)benzene; heat resistance; accuracy; high purity and luminescence in long wavelength range (red); flat display panel; television SONY CORPORATION (JP) 2011-09-27 US disclosed